[HTML][HTML] GPC3 affects the prognosis of lung adenocarcinoma and lung squamous cell carcinoma

J Ning, S Jiang, X Li, Y Wang, X Deng, Z Zhang… - BMC pulmonary …, 2021 - Springer
Abstract Background Glypican 3 (GPC3) is a heparin sulphate proteoglycan whose
expression is associated with several malignancies. However, its expression in non-small …

[HTML][HTML] Biological and clinical significance of the glypican-3 gene in human lung adenocarcinoma: An in silico analysis

RR Imon, S Aktar, N Morshed, SM Nur, R Mahtarin… - Medicine, 2023 - journals.lww.com
Abstract Glypican-3 (GPC3), a membrane-bound heparan sulfate proteoglycan, has long
been found to be dysregulated in human lung adenocarcinomas (LUADs). Nevertheless, the …

[HTML][HTML] Can glypican-3 be a disease-specific biomarker?

C Chen, X Huang, Z Ying, D Wu, Y Yu, X Wang… - Clinical and translational …, 2017 - Springer
Abstract Background Glypican-3 (GPC3) is a cell surface-bound proteoglycan which has
been identified as a potential biomarker candidate in hepatocellular carcinoma, lung …

Expression of GPC3 protein and its significance in lung squamous cell carcinoma

Q Lin, L Xiong, X Pan, J Gen, G Bao, H Sha, J Feng… - Medical oncology, 2012 - Springer
The purpose of this study was to investigate GPC3 gene expression in lung squamous cell
carcinoma tissue and its correlation with clinical and tumor characteristics. Using RT–PCR …

GPC5, a novel epigenetically silenced tumor suppressor, inhibits tumor growth by suppressing Wnt/β-catenin signaling in lung adenocarcinoma

S Yuan, Z Yu, Q Liu, M Zhang, Y Xiang, N Wu, L Wu… - Oncogene, 2016 - nature.com
Abstract Glypican-5 (GPC5) is a member of the heparin sulfate proteoglycans. Previous
studies of GPC5 in lung tumorigenesis showed conflicting results. In this study, we confirmed …

[PDF][PDF] Differential expression of glypican-3 (GPC3) in lung squamous cell carcinoma and lung adenocarcinoma and its clinical significance

X Yu, Y Li, SW Chen, Y Shi, F Xu - Genet Mol Res, 2015 - funpecrp.com.br
In this study, we examined the expression of glypican-3 (GPC3) in the 2 most common
histological types of lung cancer, squamous cell carcinoma and adenocarcinoma, and …

Glypican-3 promotes cell proliferation and tumorigenesis through up-regulation of β-catenin expression in lung squamous cell carcinoma

D Wang, Y Gao, Y Zhang, L Wang… - Bioscience Reports, 2019 - portlandpress.com
As a cell surface proteoglycan anchored by glycosyl-phosphatidylinositol, Glypican-3
(GPC3) is reported to be highly expressed in hepatocellular carcinoma (HCC) and to …

[HTML][HTML] The overexpression of glypican-5 promotes cancer cell migration and is associated with shorter overall survival in non-small cell lung cancer

YAN Li, L Miao, H Cai, J Ding, Y Xiao… - Oncology …, 2013 - spandidos-publications.com
Although the correlation between glypican-5 (GPC5) and lung cancer is well known, the
effect of GPC5 expression on non-small cell lung cancer (NSCLC) survival remains to be …

[HTML][HTML] The expression, regulation, and biomarker potential of glypican-1 in cancer

S Wang, Y Qiu, B Bai - Frontiers in oncology, 2019 - frontiersin.org
Glypican-1 (GPC-1) and other glypicans are a family of heparan sulfate proteoglycans.
These proteins are highly expressed on the cell membrane and in the extracellular matrix …

GPC5 gene and its related pathways in lung cancer

Y Li, P Yang - Journal of thoracic oncology, 2011 - jto.org
Recently, a five-center collaborative study1 reported that genetic variations of glypican-5
(GPC5) may significantly contribute to an increased risk of lung cancer in never smokers …