Left ventricular remodeling after myocardial infarction involves activation of the renin-
angiotensin-aldosterone system. Recently, the biallelic− 344T/C polymorphism of the …

Several polymorphisms in genes of the renin-angiotensin-aldosterone system have been
found to have pleiotropic effects on cardiovascular disorders. Recently, a polymorphism …

Objectives: The aim of our study was to evaluate the relationship between aldosterone
synthase gene polymorphism and cardiac dimensions in essential hypertension …

OBJECTIVES This study examined the association between the− 344 C/T polymorphism of
the human aldosterone synthase promoter and left ventricular structure in arterial …

Background—Aldosterone has direct and indirect effects on the heart, and genetic variations
in aldosterone synthesis could therefore influence cardiac structure and function. Such …

Background: Aldosterone plays an important role in development of left ventricular (LV)
hypertrophy and myocardial fibrosis. We assessed the influence of the T‐344C …

Background Aldosterone has essential roles in regulating intravascular volume and blood
pressure, and is suggested to influence cardiac structure. However, the association of …

The aldosterone synthase gene (CYP11B2) is an important candidate gene region in
essential hypertension. We therefore studied the association of-344T/C polymorphism of the …

A common polymorphism exists for the aldosterone synthase (CYP11B2) gene at position
344 (C-344-T). The 344-C allele has been associated with increased aldosterone synthase …

ABSTRACT Background and Objectives: Essential hypertension is a complex progressive
cardiovascular disorder. Renin–angiotensin aldosterone system (RAAS) plays a major role …