[图书][B] Pharmaceutical crystals: science and engineering
T Li, A Mattei - 2018 - books.google.com
An important resource that puts the focus on understanding and handling of organic crystals
in drug development Since a majority of pharmaceutical solid-state materials are organic …
in drug development Since a majority of pharmaceutical solid-state materials are organic …
Crystal structures of drugs: advances in determination, prediction and engineering
S Datta, DJW Grant - Nature Reviews Drug Discovery, 2004 - nature.com
Most marketed pharmaceuticals consist of molecular crystals. The arrangement of the
molecules in a crystal determines its physical properties and, in certain cases, its chemical …
molecules in a crystal determines its physical properties and, in certain cases, its chemical …
[PDF][PDF] Expanding the scope of crystal form evaluation in pharmaceutical science
ML Peterson, MB Hickey, MJ Zaworotko… - J. Pharm. Pharm …, 2006 - researchgate.net
The commentary seeks to provide a brief history and perspective on the importance of
crystal forms of pharmaceuticals as a means of achieving performance criteria. The …
crystal forms of pharmaceuticals as a means of achieving performance criteria. The …
[图书][B] Crystal Engineering of Multi-Component Crystal Forms: The Opportunities and Challenges in Design
HD Clarke - 2012 - search.proquest.com
There is heightened interest to diversify the range of crystal forms exhibited by active
pharmaceutical ingredients (APIs) in the pharmaceutical industry. The crystal form can be …
pharmaceutical ingredients (APIs) in the pharmaceutical industry. The crystal form can be …
Engineering of pharmaceutical materials: an industrial perspective
K Chow, HHY Tong, S Lum, AHL Chow - Journal of pharmaceutical …, 2008 - Elsevier
Crystal engineering provides a rational approach to solving formulation, processing and
product performance problems. This review discusses how the concept of crystal …
product performance problems. This review discusses how the concept of crystal …
Novel challenges in crystal engineering: polymorphs and new crystal forms of active pharmaceutical ingredients
Crystal engineering and co-crystallization have evolved in recent years and gained a
special interest not only in academia but also in the pharmaceutical field as it has been …
special interest not only in academia but also in the pharmaceutical field as it has been …
Crystal engineering and crystallography in the pharmaceutical industry
MB Hickey, Ö Almarsson, ML Peterson - CrystEngComm, 2012 - pubs.rsc.org
The value of pharmaceuticals depends on their function in treating and preventing disease.
The complex structures of drugs and their biological targets, as well as the intricate …
The complex structures of drugs and their biological targets, as well as the intricate …
Polymorphic crystal forms and cocrystals in drug delivery (crystal engineering)
N Shan, MJ Zaworotko - Burger's Medicinal Chemistry and …, 2003 - Wiley Online Library
Active pharmaceutical ingredients, APIs, are most conveniently developed and delivered
orally as solid dosage forms that contain a defined crystalline form of an API. This means …
orally as solid dosage forms that contain a defined crystalline form of an API. This means …
Crystal engineering to design of solids: from single to multicomponent organic materials
AM Araya-Sibaja, C Fandaruff… - Mini-Reviews in …, 2020 - ingentaconnect.com
Primarily composed of organic molecules, pharmaceutical materials, including drugs and
excipients, frequently exhibit physicochemical properties that can affect the formulation …
excipients, frequently exhibit physicochemical properties that can affect the formulation …
Re:“Crystal engineering in the regulatory and patent literature of pharmaceutical solid forms”
D Braga, F Grepioni, A Gavezzotti… - Crystal Growth & …, 2017 - ACS Publications
This contribution was prompted in response to the recent Perspective by Desiraju and
Nangia (hereafter DN). 1 The somewhat unconventional format used here is consistent with …
Nangia (hereafter DN). 1 The somewhat unconventional format used here is consistent with …