Surfactants in acute respiratory distress syndrome in infants and children: past, present and future

A Amigoni, A Pettenazzo, V Stritoni, M Circelli - Clinical drug investigation, 2017 - Springer
There is a lack of definitive data on the effective management of acute respiratory distress
syndrome (ARDS) in infants and children. The development and validation of the Berlin …

Treatment of acute (adult) respiratory distress syndrome

HW Taeusch - Neonatology, 2000 - karger.com
The treatment of neonatal respiratory distress syndrome with surfactant represents a
successful culmination of decades of basic and clinical research. In many babies, respiratory …

Surfactant for respiratory distress syndrome: are there important clinical differences among preparations?

S Sinha, F Moya, SM Donn - Current opinion in pediatrics, 2007 - journals.lww.com
Surfactant for respiratory distress syndrome: are there impo... : Current Opinion in Pediatrics
Surfactant for respiratory distress syndrome: are there important clinical differences among …

Exogenous surfactant therapy for ARDS

A Maruscak, JF Lewis - Expert Opinion on Investigational Drugs, 2006 - Taylor & Francis
Regardless of the cause, a common pathophysiological feature of patients with acute
respiratory distress syndrome is a dysfunction of the endogenous surfactant system …

Lung surfactants for neonatal respiratory distress syndrome: animal-derived or synthetic agents?

GK Suresh, RF Soll - Pediatric Drugs, 2002 - Springer
Exogenous surfactant therapy is widely used in the management of neonatal respiratory
distress syndrome. Two types of surfactants are available: synthetic surfactants, and those …

Surfactant for pediatric acute lung injury

DF Willson, PR Chess, RH Notter - Pediatric Clinics of North America, 2008 - Elsevier
This article reviews exogenous surfactant therapy and its use in mitigating acute lung injury
(ALI) and the acute respiratory distress syndrome (ARDS) in infants, children, and adults …

Exogenous surfactant therapy for pediatric patients with acute respiratory distress syndrome

JF Lewis, JS Dhillon, RN Singh… - Canadian …, 1997 - Wiley Online Library
Exogenous surfactant administration is currently being tested in patients with the acute
respiratory distress syndrome (ARDS). The results of the studies have varied because …

Randomized trial comparing two natural surfactants (Survanta vs. bLES) for treatment of neonatal respiratory distress syndrome

BCC Lam, YK Ng, KY Wong - Pediatric pulmonology, 2005 - Wiley Online Library
Exogenous surfactants have been used as an effective treatment of neonatal respiratory
distress syndrome (RDS). Different preparations of surfactant carry different biophysical and …

Did reduced alveolar delivery of surfactant contribute to negative results in adults with acute respiratory distress syndrome?

JB Grotberg, M Filoche, DF Willson… - American Journal of …, 2017 - atsjournals.org
The efficacy of surfactant replacement therapy for pediatric and adult lung injuries has been
an ongoing area of investigation for more than 25 years. Surfactant therapy is lifesaving in …

Surfactant for respiratory distress syndrome

A Jobe - Neoreviews, 2014 - publications.aap.org
Surfactant treatment is standard of care for infants who have respiratory distress syndrome
(RDS). However, many practical questions remain about what RDS is, and who should be …