Involvement of brain-derived neurotrophic factor signaling in the pathogenesis of stress-related brain diseases
T Numakawa, R Kajihara - Frontiers in Molecular Neuroscience, 2023 - frontiersin.org
Neurotrophins including brain-derived neurotrophic factor, BDNF, have critical roles in
neuronal differentiation, cell survival, and synaptic function in the peripheral and central …
neuronal differentiation, cell survival, and synaptic function in the peripheral and central …
The role of neurotrophin signaling in age-related cognitive decline and cognitive diseases
T Numakawa, H Odaka - International Journal of Molecular Sciences, 2022 - mdpi.com
Neurotrophins are a family of secreted proteins expressed in the peripheral nervous system
and the central nervous system that support neuronal survival, synaptic plasticity, and …
and the central nervous system that support neuronal survival, synaptic plasticity, and …
Actions of brain-derived neurotrophin factor in the neurogenesis and neuronal function, and its involvement in the pathophysiology of brain diseases
T Numakawa, H Odaka, N Adachi - International journal of molecular …, 2018 - mdpi.com
It is well known that brain-derived neurotrophic factor, BDNF, has an important role in a
variety of neuronal aspects, such as differentiation, maturation, and synaptic function in the …
variety of neuronal aspects, such as differentiation, maturation, and synaptic function in the …
Brain-derived neurotropic factor in neurodegenerative disorders
Globally, neurodegenerative diseases cause a significant degree of disability and distress.
Brain-derived neurotrophic factor (BDNF), primarily found in the brain, has a substantial role …
Brain-derived neurotrophic factor (BDNF), primarily found in the brain, has a substantial role …
The role of brain derived neurotrophic factor in central nervous system
Brain derived neurotrophic factor (BDNF) has multiple biological functions which are
mediated by the activation of two receptors, tropomyosin receptor kinase B (TrkB) receptor …
mediated by the activation of two receptors, tropomyosin receptor kinase B (TrkB) receptor …
[HTML][HTML] Functional interactions between steroid hormones and neurotrophin BDNF
T Numakawa, D Yokomaku, M Richards… - World Journal of …, 2010 - ncbi.nlm.nih.gov
Brain-derived neurotrophic factor (BDNF), a critical neurotrophin, regulates many neuronal
aspects including cell differentiation, cell survival, neurotransmission, and synaptic plasticity …
aspects including cell differentiation, cell survival, neurotransmission, and synaptic plasticity …
TrkB/BDNF signaling pathway and its small molecular agonists in CNS injury
Y Wang, J Liang, B Xu, J Yang, Z Wu, L Cheng - Life Sciences, 2023 - Elsevier
As one of the most prevalent neurotrophic factors in the central nervous system (CNS), brain-
derived neurotrophic factor (BDNF) plays a significant role in CNS injury by binding to its …
derived neurotrophic factor (BDNF) plays a significant role in CNS injury by binding to its …
Neurotrophins and other growth factors in the pathogenesis of Alzheimer's disease
T Numakawa, R Kajihara - Life, 2023 - mdpi.com
The involvement of the changed expression/function of neurotrophic factors in the
pathogenesis of neurodegenerative diseases, including Alzheimer's disease (AD), has been …
pathogenesis of neurodegenerative diseases, including Alzheimer's disease (AD), has been …
Neurotrophin signalling: novel insights into mechanisms and pathophysiology
Neurotrophins, such as brain-derived neurotrophic factor (BDNF), are prominent regulators
of neuronal survival, growth and differentiation during development. While trophic factors are …
of neuronal survival, growth and differentiation during development. While trophic factors are …
Recent advances on the role of brain-derived neurotrophic factor (BDNF) in neurodegenerative diseases
Neurotrophins, such as brain-derived neurotrophic factor (BDNF), are essential for neuronal
survival and growth. The signaling cascades initiated by BDNF and its receptor are the key …
survival and growth. The signaling cascades initiated by BDNF and its receptor are the key …