Heparin-induced thrombocytopenia

A Greinacher, T Bakchoul, A Cuker… - Platelets in Thrombotic …, 2017 - Springer
Heparin-induced thrombocytopenia (HIT) is an adverse prothrombotic disorder caused by
an immune response to complexes of platelet factor 4 and polyanions. The clinical …

Heparin-induced thrombocytopenia

A Greinacher, TE Warkentin, BH Chong - Platelets, 2019 - Elsevier
Heparin-induced thrombocytopenia (HIT) is the most common, immune-mediated adverse
drug reaction affecting blood cells. It is of high clinical relevance, as in patients developing …

Heparin‐induced thrombocytopenia

A Greinacher - Journal of thrombosis and haemostasis, 2009 - Wiley Online Library
Heparin‐induced thrombocytopenia (HIT), typically occurring in the second week of heparin
therapy, is an antibody‐mediated adverse drug reaction associated with increased …

Heparin-induced thrombocytopenia

A Greinacher, K Althaus, K Krauel… - …, 2010 - thieme-connect.com
Heparin-induced thrombocytopenia (HIT), typically occurring in the second week of heparin
therapy, is an antibody-mediated adverse drug reaction associated with increased …

Heparin-induced thrombocytopenia: frequency and pathogenesis

A Greinacher - Pathophysiology of haemostasis and thrombosis, 2006 - karger.com
Heparin-induced thrombocytopenia (HIT) is a life-and limb-threatening prothrombotic,
immune-mediated adverse drug effect that occurs with unfractionated heparin and to a …

Heparin-induced thrombocytopenia: an overview

JG Kelton - Blood reviews, 2002 - Elsevier
Heparin-induced thrombocytopenia (HIT) is the most important immunological drug reaction
that patients face today. HIT typically develops in patients 5 days after starting heparin …

Heparin induced thrombocytopenia: diagnosis and management update

I Ahmed, A Majeed, R Powell - Postgraduate medical journal, 2007 - academic.oup.com
Heparin-induced thrombocytopenia (HIT) is a potentially devastating immune mediated
adverse drug reaction caused by the emergence of antibodies that activate platelets in the …

Heparin-induced thrombocytopenia: a contemporary clinical approach to diagnosis and management

E Shantsila, GYH Lip, BH Chong - Chest, 2009 - Elsevier
Thrombocytopenia following heparin administration can be associated with an immune
reaction, now referred to as heparin-induced thrombocytopenia. HIT is essentially a …

The biological basis of immune heparin-induced thrombocytopenia.

J Amiral, A Marfaing-Koka, M Poncz, D Meyer - Platelets, 1998 - europepmc.org
Heparin induced thrombocytopenia (HIT) remains the most severe adverse effect of heparin
therapy. Recently, new information has been uncovered regarding the pathogenesis of this …

Heparin-induced thrombocytopenia: present and future

A Cuker - Journal of thrombosis and thrombolysis, 2011 - Springer
Heparin-induced thrombocytopenia (HIT) is a prothrombotic and potentially devastating
complication of heparin therapy due to formation of platelet-activating antibodies against …