Background Rates of asthma in Jordan have been doubled in the past decade, but this
increased prevalence was not met with improved asthma control protocols. The aim of the …

Variability in response to short-acting β2-agonists (eg, albuterol) among patients with
asthma from diverse racial/ethnic groups may contribute to asthma disparities. We sought to …

OBJECTIVE: To study the effects of ADRB2 (rs1042713) gene polymorphism on therapeutic
efficacy of anticholinergic drug in the treatment for refractory asthma pediatric patients …

BACKGROUND: African Americans have worse asthma outcomes compared to whites.
Adrenoceptor beta 2, surface gene (ADRB2) Gly16Arg genotypes have been associated …

Background: Aspirin-exacerbated respiratory disease (AERD), an asthma phenotype, often
presents with severe manifestations and it remains widely underdiagnosed because of …

Abstract β2-Adrenergic receptor (β2-AR) plays a crucial role in asthma pathophysiology by
regulating, processes of the lung function, and clinical response to bronchodilators. The+ …

RATIONALE: Clara cell secretory protein 16 (CC16), encoded by SCGB1A1 gene, is a
protein produced by non-ciliated bronchial epithelial cells that participates in host defense …

We carried out a genome-wide association study (GWAS) for asthma in UK Biobank,
followed by a meta-analysis with results from the Trans-National Asthma Genetic …

Background: Beta 2-adrenergic receptor is expressed in airway smooth muscle and induces
bronchial relaxation. It is assumed that two common investigated polymorphisms of the …

Objective: Genetic background and environmental stimuli play an important role in asthma,
which is an individual's hyper-responsiveness to these stimuli leading to airway …