Polymorphisms in the promoter region of CD14 gene have been associated with asthma
and atopy although the findings between cohorts have not been uniform. We aimed at …

Aim. To study the family polymorphism of ADRB2 gene in children with bronchial asthma,
living in the city of Perm. Materials and methods. Forty four children with bronchial asthma …

Background The extent of differences between genetic risks associated with various asthma
subtypes is still unknown. To better understand the heterogeneity of asthma, we employed …

In asthma, the response to β-agonists acting at β2-adrenergic receptors (β2AR) displays
extensive interindividual variation. One effector for airway β2AR, adenylyl cyclase type 9 …

Background: ADRB2 gene can be involved into the pathogenesis of COPD and cross-talk
between other receptors at cellular level, including receptor to corticosteroids. So, the aim of …

Background The most common cystic fibrosis (CF) manifestation is the progressive chronic
obstructive pulmonary disease caused by deficiency, dysfunction, or absence of the CFTR …

Background: The association of haplotype combinations of polymorphisms at positions 16
and 27 of the β 2-adrenergic receptor (ADRB2) gene and the risk of asthma exacerbations …

In asthmatic airways, adenosine is a potent bronchoconstrictor with either pro-or anti-
inflammatory effects depending on receptor interactions. While aspirin has been suggested …

BACKGROUND: Though the associations of CD14 with asthma have already been studied,
the results of different independent studies are in conflict, mostly due to differences in the …

Objective: We performed a case-control study to investigate the association of 4 SNPs in the
ADRB2 gene with risk of asthma in children, and then conducted a meta-analysis by …