IRF-2 inhibits cancer proliferation by promoting AMER-1 transcription in human gastric cancer

YJ Chen, SN Luo, H Wu, NP Zhang, L Dong… - Journal of Translational …, 2022 - Springer
Background Interferon regulatory factor 2 (IRF-2) acts as an anti-oncogene in gastric cancer
(GC); however, the underlying mechanism remains unknown. Methods This study …

Cytoplasmic localization of IRF5 induces Wnt5a/E-cadherin degradation and promotes gastric cancer cells metastasis

J Du, C Sun, J Liu, X Wang, X Zhao, Y Wang… - Cancer Gene …, 2023 - nature.com
IRF5, a nucleoplasm shuttling protein, is a pivotal transcription factor regulating immune
system activity. It's well known that immunosuppression is involved in the development of …

IRF-2 inhibits gastric cancer invasion and migration by down-regulating MMP-1

YJ Chen, L Liang, J Li, H Wu, L Dong, TT Liu… - Digestive Diseases and …, 2020 - Springer
Purpose The interferon regulatory factor 2 (IRF-2) acted as a tumor suppressor. We
inspected IRF-2 as a predictor of prognosis in gastric cancer (GC) patients and tried to find …

[HTML][HTML] IRF6 is directly regulated by ZEB1 and ELF3, and predicts a favorable prognosis in gastric cancer

D Li, P Cheng, J Wang, X Qiu, X Zhang, L Xu… - Frontiers in …, 2019 - frontiersin.org
Interferon regulatory factor 6 (IRF6) acts as a tumor suppressor and controls cell
differentiation in ectodermal and craniofacial tissues by regulating expression of target …

ILF3 promotes gastric cancer proliferation and may be used as a prognostic marker

Y Liu, Y Li, Y Zhao, Y Liu, L Fan… - Molecular Medicine …, 2019 - spandidos-publications.com
Interleukin enhancer‑binding factor 3 (ILF3) may function as a transcriptional coactivator and
has been reported to be involved in tumor proliferation and metastasis; however, its role and …

[HTML][HTML] Rs56288038 (C/G) in 3'UTR of IRF-1 regulated by MiR-502-5p promotes gastric cancer development

B Wang, H Yang, L Shen, J Wang, W Pu… - Cellular Physiology and …, 2016 - karger.com
Background/Aims: Interferon regulatory factor 1 (IRF-1) has been shown to function as a
transcriptional activator or repressor of a variety of target genes. However, its upstream, non …

[HTML][HTML] Protein arginine methyltransferase 5-mediated epigenetic silencing of IRX1 contributes to tumorigenicity and metastasis of gastric cancer

X Liu, J Zhang, L Liu, Y Jiang, J Ji, R Yan, Z Zhu… - Biochimica et Biophysica …, 2018 - Elsevier
IRX1 is originally characterized as a tumor suppressor gene of gastric cancer (GC) by our
group based on serially original studies. However, the molecular regulatory mechanisms of …

[HTML][HTML] Prognostic value of IRF-2 expression in colorectal cancer

Z Mei, G Wang, Z Liang, A Cui, A Xu, Y Liu, C Liu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Interferon regulatory factor 2 (IRF-2) is known to play a pivotal role in the
development and progression of several malignancies. As a crucial member of interferon …

Down‐regulation of interferon regulatory factor 2 binding protein 2 suppresses gastric cancer progression by negatively regulating connective tissue growth factor

Y Yao, Y Wang, L Li, X Xiang, J Li… - Journal of Cellular …, 2019 - Wiley Online Library
Interferon regulatory factor 2 binding protein 2 (IRF2BP2) is a transcriptional repressor
involved in regulating gene expression and other biological processes, including …

The transcription factor IRF9 promotes colorectal cancer via modulating the IL-6/STAT3 signaling axis

BR Sharma, R Karki, B Sundaram, Y Wang, P Vogel… - Cancers, 2022 - mdpi.com
Simple Summary Colorectal cancer (CRC) is the second most common cause of cancer-
related death worldwide. While the exact causes and prognosis of CRC are complex …