Throughout the body, damage to peripheral nerves normally involved in nociception may
produce a constellation of symptoms—including irritation, itchiness and pain. The …

As the biological alarm of impending or actual tissue damage, pain is essential for our
survival. However, when it is initiated and/or sustained by dysfunctional elements in the …

Corneal neuropathic pain (CNP) is a poorly defined disease entity characterised by an
aberrant pain response to normally non-painful stimuli and categorised into having …

Recent data suggest that corneal somatosensory dysfunction may be the underlying cause
of severe dry eye symptoms in the absence of ocular surface pathology seen in a subset of …

Ocular surface pain is a frequent cause of visits to an eye care provider and has a
substantial impact on healthcare cost, yet a complete understanding of its causative factors …

Dry eye has gained recognition as a public health problem given its prevalence, morbidity,
and cost implications. Dry eye can have a variety of symptoms including blurred vision …

The richly innervated corneal tissue is one of the most powerful pain generators in the body.
Corneal neuropathic pain results from dysfunctional nerves causing perceptions such as …

Objective. Dry eye is a multi-factorial disorder that manifests with painful ocular symptoms
and visual disturbances, which can only be partly attributed to tear dysfunction. This disorder …

Dry eye is a common, multifactorial disease currently diagnosed by a combination of
symptoms and signs. Its epidemiology and clinical presentation have many similarities with …

Objective This paper reviews ocular pain with the main focus on ocular surface discomfort
and dry eye pain. Anatomy, physiology, epidemiology, assessment, and treatment are …