Rare earth coordination chemistry in action: Exploring the optical and magnetic properties of the lanthanides in bioscience while challenging current theories

D Parker - Handbook on the Physics and Chemistry of Rare …, 2016 - Elsevier
In the 1980s, developments in healthcare led to the introduction of gadolinium complexes as
contrast agents for magnetic resonance imaging and targeted radiotherapeutic agents …

Lanthanides: applications in cancer diagnosis and therapy: miniperspective

RD Teo, J Termini, HB Gray - Journal of medicinal chemistry, 2016 - ACS Publications
Lanthanide complexes are of increasing importance in cancer diagnosis and therapy, owing
to the versatile chemical and magnetic properties of the lanthanide-ion 4f electronic …

How the ligand field in lanthanide coordination complexes determines magnetic susceptibility anisotropy, paramagnetic NMR shift, and relaxation behavior

D Parker, EA Suturina, I Kuprov… - Accounts of Chemical …, 2020 - ACS Publications
Conspectus Complexes of lanthanide (III) ions are being actively studied because of their
unique ground and excited state properties and the associated optical and magnetic …

Being excited by lanthanide coordination complexes: aqua species, chirality, excited-state chemistry, and exchange dynamics

D Parker, RS Dickins, H Puschmann… - Chemical …, 2002 - ACS Publications
Over the past 10 years there has been a resurgence of interest in the coordination chemistry
of lanthanide complexes in aqueous solution. Excitement in this work may be related to an …

Isoquinoline-based lanthanide complexes: bright NIR optical probes and efficient MRI agents

F Caillé, CS Bonnet, F Buron, S Villette… - Inorganic …, 2012 - ACS Publications
In the objective of developing ligands that simultaneously satisfy the requirements for MRI
contrast agents and near-infrared emitting optical probes that are suitable for imaging, three …

Recent development in lanthanide coordination compounds for biomedical imaging applications

WTK Chan, WT Wong - Polyhedron, 2014 - Elsevier
In this mini-review, we present some recent development of lanthanide complexes in
biomedical imaging, in particular MRI, optical imaging and multi-modal imaging probes …

The chemistry of lanthanides in biology: recent discoveries, emerging principles, and technological applications

JA Cotruvo Jr - ACS central science, 2019 - ACS Publications
The essential biological role of rare earth elements lay hidden until the discovery in 2011
that lanthanides are specifically incorporated into a bacterial methanol dehydrogenase. Only …

Using lanthanide ions in molecular bioimaging

AJ Amoroso, SJA Pope - Chemical Society Reviews, 2015 - pubs.rsc.org
Trivalent lanthanide ions offer remarkable opportunities in the design of bioimaging agents:
this review presents an accessible discussion of their application in both optical and …

Lanthanide complexes as redox and ROS/RNS probes: A new paradigm that makes use of redox-reactive and redox non-innocent ligands

DMD Leguerrier, R Barré, JK Molloy… - Coordination Chemistry …, 2021 - Elsevier
Lanthanides complexes are indispensable in fields related to medicine and biology. Their
success lies in the great number of unpaired electrons (4f 7 configuration of the Gd 3+ ion) …

Lanthanide (III) chelates for NMR biomedical applications

S Aime, M Botta, M Fasano, E Terreno - Chemical Society Reviews, 1998 - pubs.rsc.org
The peculiar magnetic properties of lanthanide (III) ions may be exploited for the
development of powerful NMR probes for biomedical applications. GdIII chelates are in …