[HTML][HTML] MHC class II activation and interferon-γ mediate the inhibition of neutrophils and eosinophils by staphylococcal enterotoxin type A (SEA)

AP Ferreira-Duarte, AS Pinheiro-Torres… - Frontiers in cellular …, 2017 - frontiersin.org
Staphylococcal enterotoxins are classified as superantigens that act by linking T-cell
receptor with MHC class II molecules, which are expressed on classical antigen-presenting …

Staphylococcus aureus enterotoxins A and B inhibit human and mice eosinophil chemotaxis and adhesion in vitro

DM Squebola-Cola, GC De Mello, GF Anhê… - International …, 2014 - Elsevier
Staphylococcus aureus aggravates the allergic eosinophilic inflammation. We hypothesized
that Staphylococcus aureus-derived enterotoxins directly affect eosinophil functions …

Protective effects of niacinamide in staphylococcal enterotoxin-B-induced toxicity

RD LeClaire, W Kell, S Bavari, TJ Smith, RE Hunt - Toxicology, 1996 - Elsevier
Staphylococcal enterotoxins (SE) interact with major histocompatibility complex (MHC) class
II cell-surface receptors, eliciting signal transduction in antigen-presenting cells (APC) …

Putative staphylococcal enterotoxin possesses two common structural motifs for MHC-II binding

S Rahman, S Saha, SB Dasgupta, AK Das - International Journal of …, 2024 - Elsevier
Staphylococcus aureus has become a significant cause of health risks in humankind.
Staphylococcal superantigens (SAgs) or enterotoxins are the key virulent factors that can …

Activation of human γδ T cells and NK cells by Staphylococcal enterotoxins requires both monocytes and conventional T cells

M Mata Forsberg, C Arasa, W van Zwol… - Journal of Leukocyte …, 2022 - academic.oup.com
Staphylococcal enterotoxins (SE) pose a great threat to human health due to their ability to
bypass antigen presentation and activate large amounts of conventional T cells resulting in …

Staphylococcal enterotoxin A regulates bone marrow granulocyte trafficking during pulmonary inflammatory disease in mice

WM Takeshita, VO Gushiken, AP Ferreira-Duarte… - Toxicology and applied …, 2015 - Elsevier
Pulmonary neutrophil infiltration produced by Staphylococcal enterotoxin A (SEA) airway
exposure is accompanied by marked granulocyte accumulation in bone marrow (BM) …

Staphylococcal enterotoxin D is a promiscuous superantigen offering multiple modes of interactions with the MHC class II receptors

R Al-Daccak, K Mehindate, F Damdoumi… - The Journal of …, 1998 - journals.aai.org
Dimerization of MHC class II molecules on the cell surface of human THP-1 monocytic cell
line is a requirement for staphylococcal superantigen (SAG)-induced cytokine gene …

Staphylococcal enterotoxin B (SEB) activates TCR-and CD28-mediated inflammatory signals in the absence of MHC class II molecules

M Kunkl, C Amormino, S Caristi, V Tedeschi… - EUROPEAN …, 2021 - iris.uniroma1.it
The inflammatory activity of staphylococcal enterotoxin B (SEB) relies on its capacity to
trigger polyclonal T‐cell activation by binding both T‐cell receptor (TCR) and costimulatory …

Staphylococcal enterotoxin B inhibits the production of interleukin‐4 in a human mast‐cell line HMC‐1

L Ackermann, J Pelkonen, IT Harvima - Immunology, 1998 - Wiley Online Library
Staphylococcal enterotoxins belong to the recently characterized group of immunocytotropic
bacterial superantigens that are potent mitogens for human T cells. Superantigens are …

Staphylococcal enterotoxin H displays unique MHC class II-binding properties

H Nilsson, P Björk, M Dohlsten… - The Journal of …, 1999 - journals.aai.org
Staphylococcal enterotoxin H (SEH) has been described as a superantigen by sequence
homology with the SEA subfamily and briefly characterized for its in vivo activity. In this …