Locoweeds are toxic leguminous plants in Astragalus and Oxytropis genera that contain
fungal endophytes of Alternaria section Undifilum species. These fungi produce …

Locoweed plants in the southwestern United States often harbour a slow-growing
endophytic fungus, Undifilum oxytropis (Phylum: Ascomycota; Order: Pleosporales), which …

Swainsonine—a cytotoxic fungal alkaloid and a potential cancer therapy drug—is produced
by the insect pathogen and plant symbiont Metarhizium robertsii, the clover pathogen …

Swainsonine is a cytotoxic alkaloid produced by fungi. Genome sequence analyses
revealed that these fungi share an orthologous gene cluster, SWN, necessary for …

The legume Oxytropis sericea hosts a fungal endophyte, Alternaria oxytropis, which
produces secondary metabolites (SM), including the toxin swainsonine. Polyketide synthase …

Legumes belonging to the Astragalus, Oxytropis, and Swainsona genera have been noted
by ranchers in the Americas, Asia, and Australia to cause a neurologic disease often …

Swainsonine (SW) is the principal toxic ingredient of locoweed plants that causes locoism
characterized by a disorder of the nervous system. It has also received widespread attention …

The indolizidine alkaloid-swainsonine (SW) is the main toxic component of locoweeds and
the main cause of locoweed poisoning in grazing animals. The endophytic fungi, Alternaria …

Swainsonine, an indolizidine alkaloid with significant physiological activity, is an α-
mannosidase and mannosidase II inhibitor that alters glycoprotein processing and causes …

Swainsonine (SW) was first isolated from Swainsona canescens, and then identified in
several Astragalus and Oxytropis species, synthesized by the endophytic fungus Alternaria …