Pendrin: linking acid base to blood pressure

F Brazier, N Cornière, N Picard, R Chambrey… - … -European Journal of …, 2024 - Springer
Abstract Pendrin (SLC26A4) is an anion exchanger from the SLC26 transporter family which
is mutated in human patients affected by Pendred syndrome, an autosomal recessive …

[HTML][HTML] Role of pendrin in acid-base balance

JH Chang, S Kim - Electrolytes & Blood Pressure: E & BP, 2009 - ncbi.nlm.nih.gov
Abstract Pendrin (SLC26A4) is a Na+-independent Cl-/HCO 3-exchanger which is
expressed in the apical membranes of type B and non-A, non-B intercalated cells within the …

Regulation of pendrin by pH: dependence on glycosylation

A Azroyan, K Laghmani, G Crambert… - Biochemical …, 2011 - portlandpress.com
Mutations in the anion exchanger pendrin are responsible for Pendred syndrome, an
autosomal recessive disease characterized by deafness and goitre. Pendrin is highly …

[HTML][HTML] Regulation of the expression of the Cl-/anion exchanger pendrin in mouse kidney by acid-base status

CA Wagner, KE Finberg, PA Stehberger, RP Lifton… - Kidney international, 2002 - Elsevier
Regulation of the expression of the Cl-/anion exchanger pendrin in mouse kidney by acid-
base status. Background Pendrin belongs to a superfamily of Cl-/anion exchangers and is …

The multiple roles of pendrin in the kidney

M Soleimani - Nephrology Dialysis Transplantation, 2015 - academic.oup.com
Abstract The C l−/HC O 3− exchanger pendrin (SLC26A4, PDS) is located on the apical
membrane of B-intercalated cells in the kidney cortical collecting duct and the connecting …

The anion exchanger pendrin (SLC26A4) and renal acid-base homeostasis

CA Wagner, N Mohebbi, G Capasso… - Cellular Physiology and …, 2011 - karger.com
The anion exchanger pendrin (Pds, SLC26A4) transports various anions including
bicarbonate, chloride and iodide. In the kidney, pendrin is exclusively expressed on the …

Impact of bicarbonate, ammonium chloride, and acetazolamide on hepatic and renal SLC26A4 expression

I Alesutan, A Daryadel, N Mohebbi, L Pelzl… - Cellular Physiology and …, 2011 - karger.com
SLC26A4 encodes pendrin, a transporter exchanging anions such as chloride, bicarbonate,
and iodide. Loss of function mutations of SLC26A4 cause Pendred syndrome characterized …

Pendrin in the mouse kidney is primarily regulated by Cl excretion but also by systemic metabolic acidosis

P Hafner, R Grimaldi, P Capuano… - … of Physiology-Cell …, 2008 - journals.physiology.org
The Cl−/anion exchanger pendrin (SLC26A4) is expressed on the apical side of renal non-
type A intercalated cells. The abundance of pendrin is reduced during metabolic acidosis …

The role of pendrin in renal physiology

SM Wall, Y Lazo-Fernandez - Annual review of physiology, 2015 - annualreviews.org
Pendrin is a Na+-independent Cl−/HCO3− exchanger that localizes to type B and non-A,
non-B intercalated cells, which are expressed within the aldosterone-sensitive region of the …

The pendrin polypeptide

S Dossena, E Bernardinelli, AK Sharma… - The Role of Pendrin in …, 2017 - Springer
Abstract Pendrin (SLC26A4) is an electroneutral anion exchanger in which function-altering
mutations cause inherited forms of non-syndromic (DFNB4) and syndromic deafness …