Selective progesterone receptor modulators for fertility preservation in women with symptomatic uterine fibroids

M Ali, A Al-Hendy - Biology of reproduction, 2017 - academic.oup.com
Uterine fibroids (UFs, AKA leiomyoma) are the most important benign neoplastic threat to
women's health, with costs up to hundreds of billions of health care dollars worldwide …

Ulipristal acetate: a novel option for the medical management of symptomatic uterine fibroids

VS Talaulikar, IT Manyonda - Advances in therapy, 2012 - Springer
Fibroids, the most common tumor in women of reproductive age, impact negatively on
women's health and quality of life, and have significant cost implications for their …

Uterine fibroid management: from the present to the future

J Donnez, MM Dolmans - Human reproduction update, 2016 - academic.oup.com
Uterine fibroids (also known as leiomyomas or myomas) are the most common form of
benign uterine tumors. Clinical presentations include abnormal bleeding, pelvic masses …

[HTML][HTML] The past, present, and future of selective progesterone receptor modulators in the management of uterine fibroids

SS Singh, L Belland, N Leyland… - American Journal of …, 2018 - Elsevier
Uterine fibroids are common in women of reproductive age and can have a significant
impact on quality of life and fertility. Although a number of international …

Ulipristal acetate: a review in symptomatic uterine fibroids

KP Garnock-Jones, ST Duggan - Drugs, 2017 - Springer
Oral ulipristal acetate (Esmya®; Fibristal®), a synthetic selective progesterone receptor
modulator, is the first selective progesterone modulator to be approved for the treatment of …

Current approaches to overcome the side effects of GnRH analogs in the treatment of patients with uterine fibroids

M Ali, M Raslan, M Ciebiera, K Zaręba… - Expert opinion on drug …, 2022 - Taylor & Francis
ABSTRACT Introduction: Uterine fibroids (UFs) are the most prevalent benign neoplastic
threat originating from myometria of reproductive age women, with a profound financial load …

Ulipristal acetate: a novel pharmacological approach for the treatment of uterine fibroids

N Biglia, S Carinelli, A Maiorana… - Drug design …, 2014 - Taylor & Francis
Uterine fibroids are the most common benign tumors of the female genital tract. The
management of symptomatic fibroids has traditionally been surgical; however, alternative …

Uterine fibroid management: Today and tomorrow

MM Dolmans, J Donnez, L Fellah - Journal of Obstetrics and …, 2019 - Wiley Online Library
Current treatments for fibroids are mainly surgical and expensive, so alternatives need to be
found. It is, therefore, vital to develop and evaluate alternatives to surgical procedures …

Successes and failures of uterine leiomyoma drug discovery

M Ali, ZT Chaudhry, A Al-Hendy - Expert Opinion on Drug …, 2018 - Taylor & Francis
Introduction: To-date, the only cure for symptomatic uterine fibroids (UFs) is surgical
intervention. However, surgery may eliminate the hope of future pregnancies; moreover, the …

New and emerging therapies for uterine fibroids

K Fritton, MA Borahay - Seminars in reproductive medicine, 2017 - thieme-connect.com
The pain, bleeding, and anemia associated with uterine fibroids debilitate many women. In
addition to limited efficacy, the side effects of the currently used medical therapies prevent …