The human immortalized brain endothelial cell line hCMEC/D3 is considered a simple in-
vitro model of the blood–brain-barrier. Our aim was to characterize changes in the …

The blood− brain barrier (BBB) is formed by endothelial cells of cerebral microvessels
sealed by tight junctions. Ischemic brain injury is known to initiate a series of biochemical …

In vivo human brain extracellular fluids (ECF) of acute stroke patients were investigated to
assess the changes in protein levels associated with ischemic damages. Microdialysates …

(1) Background: The aim of this dynamic-LC/MS-human-serum-proteomic-study was to
identify potential proteins-candidates for biomarkers of acute ischemic stroke, their changes …

Although stroke is among the most common causes of death and chronic disability
worldwide, the proteome of the ischemic human brain remains unknown. Only a few studies …

Identifying new biomarkers beyond the established risk factors that make it possible to
predict and prevent ischemic stroke has great significance. Extracellular vesicles are …

Background and purposes Recent developments in high-throughput proteomic approach
have shown the potential to discover biomarkers for diagnosing acute stroke and to …

Aim: This study aimed to identify plasma protein changes in a rat model of ischemic stroke
using a proteomic approach. Materials & Methods: Four male Sprague–Dawley rats (3–6 …

Novel therapies and biomarkers are needed for the treatment of acute ischemic stroke (AIS).
This study aimed to provide comprehensive insights into the dynamic proteome changes …

Acute ischemic stroke (AIS) is a devastating cerebrovascular disorder that leads to
permanent physical and neurological disabilities in adults worldwide. Proteins associated …