To complement a project towards the development of real-time optical biopsy for brain tissue
discrimination and surgical resection guidance, the optical properties of various brain …

The concept of using diffuse reflectance spectroscopy to distinguish intraoperatively
between pediatric brain tumors and normal brain parenchyma at the edge of resection …

Parkinson's disease (PD) is a chronic, progressive disease involving the globus pallidus
(GP), which is a gray matter mass, surrounded by white matter deep within the brain. During …

Local and superficial near-infrared (NIR) optical-property characterization of turbid biological
tissues can be achieved by measurement of spatially resolved diffuse reflectance at small …

Neuro‐oncology surgery would benefit from detailed intraoperative tissue characterization
provided by noncontact, contrast‐agent‐free, noninvasive optical imaging methods. In …

Diffuse optical spectroscopy (DOS) provides a powerful tool for fast and noninvasive disease
diagnosis. The ability to leverage DOS to accurately quantify tissue optical parameters …

Optical spectroscopy for brain tumor demarcation was investigated in this study.
Fluorescence and diffuse reflectance spectra were measured from normal and tumorous …

Time-resolved and spatially resolved measurements of the diffuse reflectance from
biological tissue are two well-established techniques for extracting the reduced scattering …

Glial tumors grow diffusely in the brain. Survival is correlated to the extent of tumor removal,
but tumor borders are often invisible. Resection beyond the borders as defined by …

A key challenge of central nervous system tumor surgery is to discriminate between brain
regions infiltrated by tumor cells and surrounding healthy tissue. Although monitoring of …