Long noncoding RNA in digestive tract cancers: function, mechanism, and potential biomarker

S Zeng, YF Xiao, B Tang, CJ Hu, R Xie, SM Yang… - The …, 2015 - academic.oup.com
Digestive tract cancers (DTCs) are a leading cause of cancer-related death worldwide.
Current therapeutic tools for advanced stage DTCs have limitations, and patients with early …

Long noncoding RNAs in digestive system cancers: Functional roles, molecular mechanisms, and clinical implications

M Fu, C Zou, L Pan, W Liang, H Qian… - Oncology …, 2016 - spandidos-publications.com
Long noncoding RNAs (lncRNAs) are emerging as new players in various diseases
including cancer. LncRNAs have been shown to play multifaceted roles in the development …

The functional role of long non-coding RNA in digestive system carcinomas

GY Wang, YY Zhu, YQ Zhang - Bulletin Du Cancer, 2014 - Elsevier
In recent years, long non-coding RNAs (lncRNAs) are emerging as either oncogenes or
tumor suppressor genes. Recent evidences suggest that lncRNAs play a very important role …

Long noncoding RNAs in gastrointestinal cancer: Tumor suppression versus tumor promotion

M Khajehdehi, M Khalaj-Kondori, T Ghasemi… - Digestive diseases and …, 2021 - Springer
Approximately 80% of the human genome harbors biochemical marks of active transcription
that its majority transcribes to noncoding RNAs, namely long noncoding RNAs (lncRNAs) …

Long non-coding RNAs: crucial regulators of gastrointestinal cancer cell proliferation

J Chen, S Liu, X Hu - Cell death discovery, 2018 - nature.com
Studies of long non-coding RNAs (lncRNAs) have been prevalent in the field of non-coding
RNA regulation in recent years. LncRNAs exert crucial effects on malignant cell processes in …

Long non-coding RNAs in colorectal cancer: novel oncogenic mechanisms and promising clinical applications

Y Yang, X Yan, X Li, Y Ma, A Goel - Cancer letters, 2021 - Elsevier
Colorectal cancer (CRC) is the third most common malignancy and ranks as the second
leading cause of cancer-related deaths worldwide. Despite the improvements in CRC …

[HTML][HTML] Long non-coding RNAs in colorectal cancer: implications for pathogenesis and clinical application

M Xu, P Qi, X Du - Modern pathology, 2014 - Elsevier
Long non-coding RNAs (lncRNAs) are a class of newly identified non-coding RNA
molecules that are emerging as key regulators of tumor initiation and development …

[PDF][PDF] Regulation mechanism of long noncoding RNAs in colon cancer development and progression

X Tang, X Qiao, C Chen, Y Liu, J Zhu… - Yonsei medical …, 2019 - synapse.koreamed.org
Colorectal cancer (CRC) is the second most common cause of cancer-related death
worldwide, and its high rates of relapse and metastasis are associated with a poor …

The relevance of long noncoding RNAs in colorectal cancer biology and clinical settings

A Talebi, M Azizpour, S Agah, M Masoodi… - Journal of cancer …, 2020 - journals.lww.com
Colorectal cancer (CRC) is one of the most frequent causes of cancer-related death
worldwide. The prognosis of the malignancy and patient survival is commonly poor …

Long non-coding RNA: a potential strategy for the diagnosis and treatment of colorectal cancer

S Chen, Y Fang, L Sun, R He, B He, S Zhang - Frontiers in Oncology, 2021 - frontiersin.org
Colorectal cancer (CRC), being one of the most commonly diagnosed cancers worldwide,
endangers human health. Because the pathological mechanism of CRC is not fully …