Phytoestrogens have been investigated as natural alternatives to hormone replacement
therapy and their potential as chemopreventive agents. We investigated the effects of equol …

Breast cancer is an important public health problem worldwide and it represents the second
leading cause of cancer-related deaths among women in most industrialized countries …

The main cause of cancer death among women is breast cancer. The most common type of
breast cancer is the estrogen receptor positive breast cancer. Discovery of estrogen receptor …

The anthraquinones emodin and aloe‐emodin are abundant in rhubarb. Several lines of
evidence indicate that emodin and aloe‐emodin have estrogenic activity as phytoestrogens …

Endogenous estrogens, such as 17β-estradiol (E2), are implicated in the development of
breast cancer. The putative mechanisms by which estrogens exert the carcinogenic effects …

Estrogen, a sex hormone present in both men and women, but occurs in higher
concentrations in women. The body tightly regulates its levels, treating it akin to a toxin …

Steroidal estrogens are suggested to induce breast cancer by way of a two-tiered
mechanism, in which estrogens stimulate cell growth and proliferation and generate …

Objective To explore the effect and pathway of phytoestrogens in vitro on the growth of both
normal and malignant breast cells. Methods Normal breast MCF-10A cells and breast …

OBJECTIVE: Phytoestrogens have been reported to exhibit antiproliferation to human breast
cancer cells in vitro. We tested the phytoestrogen-rich, Pueraria mirifica against rat breast …

The oxidative metabolism of estrogens into estrogen quinones that damage DNA,
contributes to the carcinogenicity of estrogens. In order to circumvent using hormone …