[HTML][HTML] Galanin analogs prevent mortality from seizure-induced respiratory arrest in mice

R Collard, MC Aziz, K Rapp, C Cutshall… - Frontiers in Neural …, 2022 - frontiersin.org
Objective Sudden Unexpected Death in Epilepsy (SUDEP) accounts for 20% of mortality in
those with recurrent seizures. While risk factors, monitoring systems, and standard practices …

Galanin and galanin-like peptide differentially modulate neuronal activities in rat arcuate nucleus neurons

Y Dong, JP Tyszkiewicz… - Journal of …, 2006 - journals.physiology.org
Neuropeptides galanin and galanin-like peptide (GALP) share similar amino acid sequence
and presumably interact with the same group of receptors, but they differentially regulate a …

The brain galanin receptors: targets for novel antidepressant drugs

X Lu, L Sharkey, T Bartfai - CNS & Neurological Disorders …, 2007 - ingentaconnect.com
Our present view that the mood disorders involve dysfunction of monoaminergic system is a
result of important clinical and preclinical observations over the past 40 years. The …

Galanin: neurobiologic mechanisms and therapeutic potential for Alzheimer's disease

SE Counts, SE Perez, U Kahl, T Bartfai… - CNS drug …, 2001 - Wiley Online Library
The neuropeptide galanin (GAL) is widely distributed in the mammalian CNS. Several lines
of evidence suggest that GAL may play a critical role in cognitive processes such as memory …

Galanin-25 years with a multitalented neuropeptide

SA Hobson, A Bacon, CR Elliot-Hunt… - … and Molecular Life …, 2008 - search.proquest.com
The neuropeptide galanin is widely, but not ubiquitously, expressed in the adult nervous
system. Its expression is markedly upregulated in many neuronal tissues after nerve injury or …

Expression and plasticity of galanin systems in cortical neurons, oligodendrocyte progenitors and proliferative zones in normal brain and after spreading depression

PJ Shen, JA Larm, AL Gundlach - European Journal of …, 2003 - Wiley Online Library
Neocortex contains very few galanin neurons but receives a moderate galanin innervation
from various subcortical loci. Recent data suggest that galanin helps regulate the tonic …

[HTML][HTML] Pharmacological stimulation of galanin receptor 1 but not galanin receptor 2 attenuates kainic acid-induced neuronal cell death in the rat hippocampus

J Runesson, JL Groves-Chapman, K Karlsson, I Saar… - 2012 - diva-portal.org
The neuropeptide galanin is widely distributed in the central and peripheral nervous
systems. Galanin is part of a bigger family of bioactive peptides and its biological activity is …

Galanin and GALP systems in brain—molecular pharmacology, anatomy, and putative roles in physiology and pathology

AL GUNDLACH, SRF JUNGNICKEL - Handbook of biologically active …, 2006 - Elsevier
The galanin peptide family comprises two members: galanin, a widely distributed 29-to 30-
amino-acid neuropeptide discovered in 1983, and galanin-like peptide (GALP), a structurally …

[HTML][HTML] Galanin diminishes cortical spreading depolarization across rodents–A candidate for treatment?

F Gimeno-Ferrer, A Eitner, HG Schaible, F Richter - Neuroscience Letters, 2024 - Elsevier
Galanin (Gal) is a neuropeptide with the potential to ameliorate cortical spreading
depolarization (CSD), an electrophysiological phenomenon occurring after brain injury or in …

Galanin receptors as a potential target for neurological disease

K Freimann, K Kurrikoff, Ü Langel - Expert Opinion on Therapeutic …, 2015 - Taylor & Francis
Introduction: Galanin is a 29/30 amino acid long neuropeptide that is widely expressed in
the brains of many mammals. Galanin exerts its biological activities through three different G …