An efficacious vaccine is needed to control Chlamydia trachomatis infection. In the murine
model of Chlamydia muridarum genital infection, multifunctional mucosal CD4 T cells are …

The Chlamydial outer membrane complex (COMC) from the elementary body (EB) is a
protein rich insoluble outer membrane shell from which cytosolic proteins have been …

Urogenital Chlamydia serovars replicating in reproductive epithelium pose a unique
challenge to host immunity and vaccine development. Previous studies have shown that …

Implementation of a vaccine is likely the best approach to curtail Chlamydia trachomatis
infections. The aim of this study was to determine the ability of a vaccine formulated with the …

Major impediments to a Chlamydia vaccine lie in discovering T cell antigens and polarizing
adjuvants that stimulate protective immunity. We previously reported the discovery of three T …

Objectives To test vaccines, formulated with novel antigens, to protect mice against
Chlamydia infections. Methods To determine the ability of polymorphic membrane proteins …

Despite effective antimicrobial chemotherapy, control of Chlamydia trachomatis urogenital
infection will likely require a vaccine. We have assessed the protective effect of an outer …

To test several vaccines for Chlamydia trachomatis we vaccinated BALB/c and C3H/HeN
female mice with a purified preparation of the native mouse pneumonitis (MoPn) major outer …

Using a combination of affinity chromatography and tandem mass spectrometry, we recently
identified 8 MHC class II (IA b)-bound Chlamydia peptides eluted from dendritic cells (DCs) …

Pmps (Polymorphic Membrane Proteins) are a group of membrane bound surface exposed
chlamydial proteins that have been characterized as autotransporter adhesins and are …