Background MRI of hyperpolarized 129Xenon (HP 129Xe) is increasingly utilized for
investigating pulmonary function. The solubility of HP 129Xe in lung tissue, blood plasma …

Purpose The MR properties (chemical shifts and decay rates) of dissolved‐phase
hyperpolarized (HP) 129Xe are confounded by the large magnetic field inhomogeneity …

Purpose To assess the effect of lung volume on measured values and repeatability of xenon
129 (129Xe) gas uptake metrics in healthy volunteers and participants with chronic …

Purpose A novel technique is presented for retrospective estimation and removal of gas‐
phase hyperpolarized Xenon‐129 (HP 129Xe) from images of HP 129Xe dissolved in the …

During the measurement of hyperpolarized 129Xe magnetic resonance imaging (MRI), the
diffusion‐weighted imaging (DWI) technique provides valuable information for the …

Purpose Hyperpolarized 129Xe magnetic resonance imaging (MRI) using Dixon‐based
decomposition enables single‐breath imaging of 129Xe in the airspaces, interstitial barrier …

Purpose To demonstrate the feasibility of mapping gas exchange with single breath‐hold
hyperpolarized (HP) 129Xe in humans, acquiring parametric maps of lung physiology. The …

A variety of pulmonary pathologies, in particular interstitial lung diseases, are characterized
by thickening of the pulmonary blood–gas barrier, and this thickening results in reduced gas …

Background One of the central physiological functions of the lungs is to transfer inhaled
gases from the alveoli to pulmonary capillary blood. However, current measures of alveolar …

Clinical magnetic resonance imaging of the lung is technologically challenging, yet over the
past two decades hyperpolarized noble gas (3He and 129Xe) imaging has demonstrated …