Regulatory T cells (Tregs) are crucial for preserving tolerance in the body, rendering Treg
immunotherapy a promising treatment option for both organ transplants and autoimmune …

Regulatory T cells (Tregs) are crucial in maintaining tolerance. Hence, Treg immunotherapy
is an attractive therapeutic option in autoimmune diseases and organ transplantations …

Cellular therapies using regulatory T (Treg) cells are currently undergoing clinical trials for
the treatment of autoimmune diseases, transplant rejection and graft-versus-host disease. In …

T regulatory cells (Tregs) play a vital role in suppressing heightened immune response, and
thereby promote a state of immunological tolerance. Tregs modulate both innate and …

Cell therapy has emerged as an attractive therapeutic option in organ transplantation.
During the last decade, the therapeutic potency of Treg immunotherapy has been shown in …

Simple Summary Adoptive immunotherapy has emerged as an effective alternative of
mounting impact to the current standard of care in cancer, viral infections, and recently …

Transplant rejection remains a challenge especially in the field of vascularized composite
allotransplantation (VCA). To blunt the alloreactive immune response ‚stable levels of …

Organ transplants have been a life-saving form of treatment for many patients who are facing
end stage organ failure due to conditions such as diabetes, hypertension, various congenital …

Solid organ transplantation remains the treatment of choice for end‐stage organ failure.
Whilst the short‐term outcomes post‐transplant have improved in the last decades, chronic …

Recently, increased interest in the use of Tregs as adoptive cell therapy for the treatment of
autoimmune diseases and transplant rejection had led to several advances in the field …