Interpretation of transplant biopsies and immune responses following Treg cell therapy

Q Tang, SM Kang - Current opinion in organ transplantation, 2014 - journals.lww.com
Interpretation of transplant biopsies and immune responses f... : Current Opinion in Organ
Transplantation Interpretation of transplant biopsies and immune responses following Treg cell …

Adoptive Treg cell-based immunotherapy: Frontier therapeutic aspects in rheumatoid arthritis

M Zavvar, S Assadiasl, S Zargaran, M Akhtari… - …, 2020 - Taylor & Francis
The major current focus on treating rheumatoid arthritis is to put an end to long-term
treatments and instead, specifically block widespread immunosuppression by developing …

Clinical manufacturing of regulatory T cell products for adoptive cell therapy and strategies to improve therapeutic efficacy

KJ Baron, HR Turnquist - Organogenesis, 2023 - Taylor & Francis
Based on successes in preclinical animal transplant models, adoptive cell therapy (ACT)
with regulatory T cells (Tregs) is a promising modality to induce allograft tolerance or reduce …

Adoptive regulatory T cell therapy: challenges in clinical transplantation

N Safinia, P Sagoo, R Lechler… - Current Opinion in Organ …, 2010 - journals.lww.com
Adoptive regulatory T cell therapy: challenges in clinical t... : Current Opinion in Organ
Transplantation Adoptive regulatory T cell therapy: challenges in clinical transplantation : Current …

Optimizing regulatory T cells for therapeutic application in human organ transplantation

T Vaikunthanathan, N Safinia… - Current Opinion in Organ …, 2018 - journals.lww.com
Optimizing regulatory T cells for therapeutic application in... : Current Opinion in Organ
Transplantation Optimizing regulatory T cells for therapeutic application in human organ …

[HTML][HTML] Cell therapy in organ transplantation: our experience on the clinical translation of regulatory T cells

N Safinia, N Grageda, C Scottà, S Thirkell… - Frontiers in …, 2018 - frontiersin.org
Solid organ transplantation is the treatment of choice for patients with end-stage organ
dysfunction. Despite improvements in short-term outcome, long-term outcome is suboptimal …

[HTML][HTML] Therapeutic application of T regulatory cells in composite tissue allotransplantation

JH Yang, SC Eun - Journal of translational medicine, 2017 - Springer
With growing number of cases in recent years, composite tissue allotransplantation (CTA)
has been improving the quality of life of patient who seeks reconstruction and repair of …

[HTML][HTML] Regulatory T cell therapy of graft-versus-host disease: advances and challenges

M Hefazi, S Bolivar-Wagers, BR Blazar - International journal of molecular …, 2021 - mdpi.com
Graft-versus-host disease (GVHD) is the leading cause of morbidity and mortality after
allogeneic hematopoietic stem cell transplantation (allo-HSCT). Immunomodulation using …

[HTML][HTML] Identification, selection, and expansion of non-gene modified alloantigen-reactive Tregs for clinical therapeutic use

A Alzhrani, M Bottomley, K Wood, J Hester, F Issa - Cellular immunology, 2020 - Elsevier
Transplantation is limited by the need for life-long pharmacological immunosuppression,
which carries significant morbidity and mortality. Regulatory T cell (Treg) therapy holds …

Regulatory T-cell therapy in transplantation and severe autoimmunity

M Rossetti, R Spreafico - Critical Reviews™ in Immunology, 2015 - dl.begellhouse.com
Current approaches to prevent or treat transplant rejection, graft-versus-host disease and
severe autoimmunity rely on non-specific immunosuppressive drugs. Ongoing efforts aimed …