T cell-mediated immune rejection remains a barrier to successful transplantation. Polymer-
based bioengineering of cells may provide an effective means of preventing allorecognition …

Solid organ transplant (SOT) recipients require meticulously tailored immunosuppressive
regimens to minimize graft loss and mortality. Traditional approaches focus on inhibiting …

Forkhead box P3–expressing regulatory T (Treg) cells are essential for self-tolerance, with
an emerging role in tissue repair and regeneration. Their ability to traffic to tissue and …

In autoimmunity, the important and fragile balance between immunity and tolerance is
disturbed, resulting in abnormal immune responses to the body's own tissues and cells …

Graft survival has been lately improved by the introduction of efficient immunosuppressive
drugs. However, late graft loss caused by chronic rejection and the side effects of long‐term …

The discovery of regulatory T cells (Tregs) as a crucial component of peripheral down-
regulation of immunity to self and allogeneic antigens has raised legitimate hope for the …

Modulation of immunological responses to allografts following transplantation is of pivotal
importance to improving graft outcome and duration. Of the many approaches, harnessing …

Organ transplantation is currently the only effective treatment for end-stage organ failure.
However, success is limited by the immune response of the recipient to allogeneic tissues …

Adoptive transfer of T regulatory cells (Tregs) is of great interest as a novel
immunosuppressive therapy in autoimmune disorders and transplantation. Obtaining a …

Advances in immunosuppressive therapies have made tissue and organ transplantation a
common procedure in clinical medicine. However, true donor and recipient tolerance is not …