Immune-suppressive cellular immunotherapy requires large numbers of antigen-specific
regulatory T cells (Treg cells), lymphocytes that suppress certain immune responses …

Regulatory T cells (Tregs) are critical mediators of peripheral immune tolerance. Tregs
suppress immune activation against self-antigens and are the focus of cell-based therapies …

Regulatory T cells (Treg) are critical controllers of the immune response. Disturbed Treg
function results in autoimmunity, whereas in transplantation Treg are crucial in graft survival …

It has now been well documented in a variety of models that T regulatory T cells (Treg cells)
play a pivotal role in the maintenance of self-tolerance, T cell homeostasis, tumor, allergy …

Transplantation is a successful treatment for end-stage organ failure. Despite improvements
in short-term outcome, long-term survival remains suboptimal because of the morbidity and …

Cellular therapy with CD4+FOXP3+ T regulatory (Treg) cells is a promising strategy to
induce tolerance after solidorgan transplantation or prevent graft-versus-host disease after …

Adoptive therapy with regulatory T cells (Tregs) has shown great promises in many
experimental models to induce permanent graft acceptance and tolerance to alloantigens …

Regulatory T cells (Tregs) are long-lived cells that suppress immune responses in vivo in a
dominant and antigen-specific manner. Therefore, therapeutic application of Tregs to control …

Regulatory T cells (Tregs) are crucial in inducing and maintaining tolerance. This unique
capacity of Tregs, in combination with proof-of-principle in preclinical studies, highlights the …

Abstract CD4+ CD25+ Treg are pivotal for the maintenance of self‐tolerance and the
adoptive transfer of Treg is envisaged for the treatment of autoimmune diseases and the …