The fluoride ion (F) is a disturbing substance for the glucose-insulinsystem. The effects of F
have been studied in various aspects. The chronic intake ofF generates hyperglycaemia …

Endemic fluorosis is a condition resulting from prolonged ingestion of drinking water which
contains excess fluoride. Studies on rats have suggested that fluoride toxicity may produce …

Daily intake of water with fluoride concentrations O1. 5 mg/l produces insulin resistance (IR).
On the other hand, physical activity increases insulin sensitivity in the muscle. Therefore, the …

A cross-sectional study was performed to investigate the relationships between serum
fluoride levels, glucose levels, and insulin secretion in a general population. A total of 330 …

Fluoride is known to cause both local and systemic alterations in animals and humans, such
as dental fluorosis and disturbances in glucose homeostasis. The effects of fluoride are dose …

The present study was designed to investigate the role of postnatal fluoride intake on [3H]
glucose uptake and transport in rat brain and peripheral tissues. Sodium fluoride (NaF) in a …

Studies on the role of insulin and insulin receptor (InsR) in the process of skeletal fluorosis,
especially in osteogenic function, are rare. We evaluated the effect of increasing F− doses …

Excessive fluoride ion (F) intake promotes systemic metabolic alterations, such as a
decrease in insulin secretion, hyperglycemia, and insulin resistance, similar to those …

Glucose intolerance in fluorosis areas and when fluoride is administered for the treatment of
osteoporosis has been reported. Controlled fluoridation of drinking water is regarded as a …

Chronic exposure to high fluoride (F−) may lead to local tissue disturbances, known as
fluorosis. F− is an oxidising agent and a well-known reversible enzymatic inhibitor that …