Background There are a dozen studies on double or triple chronotherapy in depression
(sleep deprivation [wake therapy]+ light therapy+ sleep advance/stabilization). We …

Background The combination of sleep deprivation and light therapy, called combined
chronotherapy, may yield positive short-and long-term results, even in patients with …

Background Triple chronotherapy (wake night [one night without sleep], sleep phase
advance, and early morning bright light exposure) demonstrated rapid efficacy primarily in …

Bright light is the recommended treatment for winter seasonal affective disorder (SAD).
Previously we showed that the antidepressant effect of morning (but not evening) light was …

BACKGROUND: Light Therapy (LT) when combined with standard antidepressant treatment
for unipolar depression hastens recovery. We studied the influence of LT timing on the …

Objective To examine the efficacy of using wake and light therapy as a supplement to
standard treatment of hospitalized patients with depression. Method In this randomized …

Background Light therapy yields inconsistent results in people with non-seasonal
depression, which may in part be due to heterogeneous responses and the temporal …

There is growing evidence for combined chronotherapeutic interventions as adjunctive
treatments for major depression. However, as the treatments can be demanding, we need to …

Background The aim of the study was to examine the efficacy and safety of morning bright
light therapy (BLT) in the treatment of patients with a current major depressive episode …

Background Triple chronotherapy (sleep deprivation for 36 h, followed by 4 days of
advancing the time of sleep and daily morning bright-light therapy for 6 months) has …