[HTML][HTML] Cartilage oligomeric matrix protein as a marker of progressive liver fibrosis in biliary atresia

W Udomsinprasert, N Angkathunyakul, J Jittikoon… - Scientific Reports, 2021 - nature.com
This study aimed to determine whether mRNA and protein levels of cartilage oligomeric
matrix protein (COMP), a glycoprotein responsible for modulating homeostasis of …

[HTML][HTML] Cartilage oligomeric matrix protein: A novel non-invasive marker for assessing cirrhosis and risk of hepatocellular carcinoma

GL Norman, NK Gatselis, Z Shums… - World journal of …, 2015 - ncbi.nlm.nih.gov
AIM: To assess serum cartilage oligomeric matrix protein (COMP) as a marker of cirrhosis
and risk of progression to hepatocellular carcinoma (HCC). METHODS: A COMP enzyme …

[HTML][HTML] Persistent elevation of fibrosis biomarker cartilage oligomeric matrix protein following hepatitis C virus eradication

K Andréasson, G Jönsson, R Hesselstrand… - World Journal of …, 2019 - ncbi.nlm.nih.gov
Serum levels of cartilage oligomeric matrix protein (COMP) has been presented as a
biomarker of liver fibrosis in several cross-sectional studies. COMP is also an essential …

[HTML][HTML] Cartilage oligomeric matrix protein overexpression is an independent poor prognostic indicator in patients with intrahepatic cholangiocarcinoma

KH Ong, YY Hsieh, HY Lai, DP Sun, TJ Chen… - Scientific Reports, 2023 - nature.com
Cartilage oligomeric matrix protein (COMP) interacts with various extracellular matrix
proteins in tissues. Elevated COMP levels recently linked to worse overall survival in …

Cartilage oligomeric matrix protein participates in the pathogenesis of liver fibrosis

F Magdaleno, E Arriazu, MR de Galarreta, Y Chen… - Journal of …, 2016 - Elsevier
Background & Aims Liver fibrosis is characterized by significant accumulation of
extracellular matrix (ECM) proteins, mainly fibrillar collagen-I, as a result of persistent liver …

Cartilage oligomeric matrix protein: a new promising biomarker of liver fibrosis in chronic hepatitis C

K Andréasson, R Hesselstrand, T Saxne… - Infectious …, 2015 - Taylor & Francis
Cartilage oligomeric matrix protein (COMP) is a biomarker of fibrosis in lung and skin. In this
exploratory study we investigated the biomarker potential of COMP in chronic hepatitis C …

Cartilage oligomeric matrix protein expression in hepatocellular carcinoma and the cirrhotic liver

Y Xiao, J Kleeff, J Guo, A Gazdhar… - Journal of …, 2004 - Wiley Online Library
Background: Cartilage oligomeric matrix protein (COMP) is the fifth member of the
thrombospondin family of extracellular, calcium‐binding proteins. It was initially isolated and …

Expression of cartilage oligomeric matrix protein in periampullary adenocarcinoma is associated with pancreatobiliary-type morphology, higher levels of fibrosis and …

KS Papadakos, S Lundgren, C Gialeli, P Micke… - …, 2022 - Taylor & Francis
Cartilage oligomeric matrix protein (COMP) is an emerging regulator of tumor progression.
The aim of this study was to evaluate the expression of COMP in periampullary …

COMP serum levels: A new non-invasive biomarker of liver fibrosis in patients with chronic viral hepatitis

K Zachou, S Gabeta, Z Shums, NK Gatselis… - European Journal of …, 2017 - Elsevier
Background & aims Recently we have shown that cartilage oligomeric matrix protein
(COMP), a fibrillar collagen assembly regulator, is strongly associated with cirrhosis and …

[HTML][HTML] Decreased circulating clusterin reflects severe liver complications after hepatoportoenterostomy of biliary atresia

W Udomsinprasert, Y Poovorawan, V Chongsrisawat… - Scientific Reports, 2020 - nature.com
This study aimed to determine whether circulating levels of clusterin (CLU), an extracellular
chaperone implicated in cholestatic and fibrotic processes, are associated with clinical …