Neuroprotective effect of treatment with human albumin in permanent focal cerebral ischemia: histopathology and cortical perfusion studies
Y Liu, L Belayev, W Zhao, R Busto, A Belayev… - European journal of …, 2001 - Elsevier
In recent experimental studies, we demonstrated a highly beneficial neuroprotective effect of
moderate-to high-dose human albumin treatment of transient focal cerebral ischemia, but we …
moderate-to high-dose human albumin treatment of transient focal cerebral ischemia, but we …
[HTML][HTML] The effect of high-dose albumin therapy on local cerebral perfusion after transient focal cerebral ischemia in rats
PW Huh, L Belayev, W Zhao, R Busto, I Saul… - Brain research, 1998 - Elsevier
We have shown that high-concentration albumin therapy is markedly neuroprotective in
focal cerebral ischemia. The present study was conducted to ascertain the degree to which …
focal cerebral ischemia. The present study was conducted to ascertain the degree to which …
Human albumin therapy of acute ischemic stroke: marked neuroprotective efficacy at moderate doses and with a broad therapeutic window
L Belayev, Y Liu, W Zhao, R Busto, MD Ginsberg - Stroke, 2001 - Am Heart Assoc
Background and Purpose—We examined the neuroprotective efficacy of moderate-dose
human albumin therapy in acute focal ischemic stroke and defined the therapeutic window …
human albumin therapy in acute focal ischemic stroke and defined the therapeutic window …
Albumin therapy in acute stroke patients
Preclinical studies have recently shown that albumin has neuroprotective effects for stroke in
animal models. Thus, we sought to evaluate the effects of albumin therapy in patients with …
animal models. Thus, we sought to evaluate the effects of albumin therapy in patients with …
[HTML][HTML] Protein extravasation and cellular uptake after high-dose human-albumin treatment of transient focal cerebral ischemia in rats
M Remmers, R Schmidt-Kastner, L Belayev, B Lin… - Brain research, 1999 - Elsevier
Treatment with human albumin administered intravenously in the immediate post-ischemic
period following a 2-h period of transient focal cerebral ischemia leads to a reduction of …
period following a 2-h period of transient focal cerebral ischemia leads to a reduction of …
[HTML][HTML] Neuroprotective effect of high-dose albumin therapy against global ischemic brain injury in rats
L Belayev, I Saul, PW Huh, N Finotti, W Zhao, R Busto… - Brain research, 1999 - Elsevier
The purpose of this study was to determine whether treatment with high-dose human serum
albumin (HSA) would offer protection in a model of high-grade transient forebrain ischemia …
albumin (HSA) would offer protection in a model of high-grade transient forebrain ischemia …
Albumin therapy of transient focal cerebral ischemia: in vivo analysis of dynamic microvascular responses
L Belayev, E Pinard, H Nallet, J Seylaz, Y Liu… - Stroke, 2002 - Am Heart Assoc
Background and Purpose—To study whether intravascular or hemodynamic factors
contribute to the marked neuroprotective effect of albumin therapy in focal cerebral ischemia …
contribute to the marked neuroprotective effect of albumin therapy in focal cerebral ischemia …
[HTML][HTML] Repeated oral administration of human serum albumin protects from the cerebral ischemia in rat brain following MCAO
H Park, M Hong, GJ Jhon, Y Lee… - Experimental …, 2017 - ncbi.nlm.nih.gov
Albumin is known to have neuroprotective effects. The protein has a long half-life circulation,
and its effects can therefore persist for a long time to aid in the recovery of brain ischemia. In …
and its effects can therefore persist for a long time to aid in the recovery of brain ischemia. In …
Diffusion-weighted magnetic resonance imaging confirms marked neuroprotective efficacy of albumin therapy in focal cerebral ischemia
L Belayev, W Zhao, PM Pattany, RG Weaver, PW Huh… - Stroke, 1998 - Am Heart Assoc
Background and Purpose—We have recently shown high-dose human serum albumin
therapy to confer marked histological protection in experimental middle cerebral artery …
therapy to confer marked histological protection in experimental middle cerebral artery …
Effect of delayed albumin hemodilution on infarction volume and brain edema after transient middle cerebral artery occlusion in rats
L Belayev, R Busto, W Zhao, JA Clemens… - Journal of …, 1997 - thejns.org
✓ The authors examined the effect of delayed high-concentration albumin therapy on
ischemic injury in a highly reproducible model of middle cerebral artery (MCA) occlusion in …
ischemic injury in a highly reproducible model of middle cerebral artery (MCA) occlusion in …