Lamivudine, also widely known as 3TC belongs to a family of nucleotide/nucleoside
analogues of cytidine or cytosine that inhibits the Reverse Transcriptase (RT) of retroviruses …

Background The very limited time allowed to face the COVID-19 pandemic poses a pressing
challenge to find proper therapeutic approaches. However, synthesis and full investigation …

Background Drug repurposing is a valuable strategy for rapidly developing drugs for treating
COVID-19. This study aimed to evaluate the antiviral effect of six antiretrovirals against …

The outbreak of a novel coronavirus (SARS-CoV-2) has caused a major public health
concern across the globe. SARS-CoV-2 is the seventh coronavirus that is known to cause …

Antivirals already on the market and expertise gained from the SARS and MERS outbreaks
are gaining momentum as the most effective way to combat the coronavirus outbreak. SARS …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the coronavirus disease 2019 (COVID-19) pandemic. The virus still spreads globally through …

The rapid emergence of COVID-19 pandemics worldwide is of particular concern for fragile
populations who are more at risk of acute respiratory distress syndrome and death. Patients …

Background: Since the end of 2019, the etiologic agent SAR-CoV-2 responsible for one of
the most significant epidemics in history has caused severe global economic, social, and …

Since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at
the end of 2019, thousands of SARS-CoV-2 mutations have been increasingly observed …

The novel coronavirus SARS-CoV-2 disease “COVID-19” emerged in China and rapidly
spread to other countries; due to its rapid worldwide spread, the WHO has declared this as a …