Neural stem cell (NSC) transplantation has great therapeutic potential for
neurodegenerative diseases and central nervous system injuries. Successful NSC …

Neural tissue engineering aims at developing novel approaches for the treatment of
diseases of the nervous system, by providing a permissive environment for the growth and …

Background Neural stem cells (NSCs) play an important role in developing potential cell-
based therapeutics for neurodegenerative disease. Microfluidics has proven a powerful tool …

Microfluidics can provide unique experimental tools to visualize the development of neural
structures within a microscale device, which is followed by guidance of neurite growth in the …

We report a microfluidic array for investigating and quantitatively analyzing human neural
stem cell (hNSC) self-renewal and differentiation in an in vivo-like microenvironment. NSC …

Here, we report a unique method to quantify the effects of in vivo-like extracellular matrix
(ECM) for guiding differentiation of neural stem cells (NSCs) in three-dimensional (3D) …

Biological studies typically rely on a simple monolayer cell culture, which does not reflect the
complex functional characteristics of human tissues and organs, or their real response to …

Microfluidic-based neuron cell culture systems have recently gained a lot of attention due to
their efficiency in supporting the spatial and temporal control of cellular microenvironments …

Control of neural stem cell (NSC) self-renewal and differentiationis of great importance to
improve its therapeutic efficacy in the treatment of neurodegenerative diseases …

Axonal pathology has been clearly implicated in neurodegenerative diseases making the
compartmental culture of neurons a useful research tool. Primary neurons have already …