Effect of fecal microbiota transplantation on neurological restoration in a spinal cord injury mouse model: involvement of brain-gut axis
Y Jing, Y Yu, F Bai, L Wang, D Yang, C Zhang, C Qin… - Microbiome, 2021 - Springer
Background Spinal cord injury (SCI) patients display disruption of gut microbiome, and gut
dysbiosis exacerbate neurological impairment in SCI models. Cumulative data support an …
dysbiosis exacerbate neurological impairment in SCI models. Cumulative data support an …
Fecal microbiota transplantation exerts neuroprotective effects in a mouse spinal cord injury model by modulating the microenvironment at the lesion site
Y Jing, F Bai, L Wang, D Yang, Y Yan… - Microbiology …, 2022 - Am Soc Microbiol
The primary traumatic event that causes spinal cord injury (SCI) is followed by a progressive
secondary injury featured by vascular disruption and ischemia, inflammatory responses and …
secondary injury featured by vascular disruption and ischemia, inflammatory responses and …
Fecal microbiota transplantation is a promising method to restore gut microbiota dysbiosis and relieve neurological deficits after traumatic brain injury
D Du, W Tang, C Zhou, X Sun, Z Wei… - Oxidative medicine …, 2021 - Wiley Online Library
Background. Traumatic brain injury (TBI) can induce persistent fluctuation in the gut
microbiota makeup and abundance. The present study is aimed at determining whether …
microbiota makeup and abundance. The present study is aimed at determining whether …
Alterations in gut microbiota are related to metabolite profiles in spinal cord injury
JN Kang, ZF Sun, XY Li, XD Zhang, ZX Jin… - Neural Regeneration …, 2023 - journals.lww.com
Studies have shown that gut microbiota metabolites can enter the central nervous system via
the blood-spinal cord barrier and cause neuroinflammation, thus constituting secondary …
the blood-spinal cord barrier and cause neuroinflammation, thus constituting secondary …
Gut dysbiosis impairs recovery after spinal cord injury
The trillions of microbes that exist in the gastrointestinal tract have emerged as pivotal
regulators of mammalian development and physiology. Disruption of this gut microbiome, a …
regulators of mammalian development and physiology. Disruption of this gut microbiome, a …
Spinal cord injury and gut microbiota: A review
Y Jing, F Bai, Y Yu - Life sciences, 2021 - Elsevier
After spinal cord injury (SCI), intestinal dysfunction has a serious impact on physical and
mental health, quality of life, and social participation. Recent data from rodent and human …
mental health, quality of life, and social participation. Recent data from rodent and human …
Investigation of microbiota alterations and intestinal inflammation post-spinal cord injury in rat model
G O'Connor, E Jeffrey, D Madorma, A Marcillo… - Journal of …, 2018 - liebertpub.com
Although there has been a significant amount of research focused on the pathophysiology of
spinal cord injury (SCI), there is limited information on the consequences of SCI on remote …
spinal cord injury (SCI), there is limited information on the consequences of SCI on remote …
The microbiota-gut-brain axis participates in chronic cerebral hypoperfusion by disrupting the metabolism of short-chain fatty acids
W Xiao, J Su, X Gao, H Yang, R Weng, W Ni, Y Gu - Microbiome, 2022 - Springer
Background Chronic cerebral hypoperfusion (CCH) underlies secondary brain injury
following certain metabolic disorders and central nervous system (CNS) diseases …
following certain metabolic disorders and central nervous system (CNS) diseases …
Gut microbiota as a therapeutic target to ameliorate the biochemical, neuroanatomical, and behavioral effects of traumatic brain injuries
Current efficacious treatments for traumatic brain injury (TBI) are lacking. Establishment of a
protective gut microbiota population offers a compelling therapeutic avenue, as brain injury …
protective gut microbiota population offers a compelling therapeutic avenue, as brain injury …
Traumatic spinal cord injury and the gut microbiota: current insights and future challenges
T Jogia, MJ Ruitenberg - Frontiers in immunology, 2020 - frontiersin.org
Individuals with traumatic spinal cord injury (SCI) suffer from numerous peripheral
complications in addition to the long-term paralysis that results from disrupted neural …
complications in addition to the long-term paralysis that results from disrupted neural …