Magnetic activated cell sorting: an effective method for reduction of sperm DNA fragmentation in varicocele men prior to assisted reproductive techniques

T Degheidy, H Abdelfattah, A Seif, FK Albuz… - Andrologia, 2015 - Wiley Online Library
Semen parameters of varicocele men have been usually suspected to exhibit higher levels
of abnormalities including DNA fragmentation, reactive oxygen species (ROS) and apoptotic …

Magnetic-activated cell sorting is not completely effective at reducing sperm DNA fragmentation

MG Martínez, P Sánchez-Martín… - Journal of Assisted …, 2018 - Springer
Purpose To determine whether there is a homogeneous reduction of sperm DNA
fragmentation (SDF) in sperm samples recovered from the MACS procedure, compared to …

[PDF][PDF] High pregnancy and implantation rates can be obtained using magnetic-activated cell sorting (MACS) to selection spermatozoa in patients with high levels of …

J García-Ferreyra, L Villegas, R Romero… - JFIV Reprod. Med …, 2014 - ihrindia.com
Purpose: DNA fragmentation in spermatozoa has been associated with poor semen quality,
low fertilization rates, impaired preimplantation development, and high miscarriage rates …

Microscopic varicocelectomy significantly decreases the sperm DNA fragmentation index in patients with infertility

TC Kadioglu, E Aliyev, M Celtik - BioMed research international, 2014 - Wiley Online Library
Background. Varicocele is associated with high levels of DNA damage in spermatozoa due
to oxidative stress and elevated levels of sperm DNA fragmentation, which has been …

Magnetic‐activated cell sorting before density gradient centrifugation improves recovery of high‐quality spermatozoa

TS Berteli, MG Da Broi, WP Martins, RA Ferriani… - …, 2017 - Wiley Online Library
Recent studies have evaluated the use of magnetic‐activated cell sorting (MACS) to reduce
apoptotic spermatozoa and improve sperm quality. However, the efficiency of using MACS …

[HTML][HTML] Magnetic-activated cell sorting of nonapoptotic spermatozoa with a high DNA fragmentation index improves the live birth rate and decreases transfer cycles of …

J Mei, LJ Chen, XX Zhu, W Yu, QQ Gao… - Asian Journal of …, 2022 - journals.lww.com
The present study aimed to evaluate the clinical outcomes of magnetic-activated cell sorting
(MACS) in sperm preparation for male subjects with a sperm DNA fragmentation index …

Acridine orange and flow cytometry: which is better to measure the effect of varicocele on sperm DNA integrity?

EEM Mohammed, E Mosad, AM Zahran… - Advances in …, 2015 - Wiley Online Library
We evaluated the effect of varicocelectomy on semen parameters and levels of sperm DNA
damage in infertile men. A total of 75 infertile men with varicocele and 40 fertile men …

Multiple determinations of sperm DNA fragmentation show that varicocelectomy is not indicated for infertile patients with subclinical varicocele

A García-Peiró, J Ribas-Maynou… - BioMed Research …, 2014 - Wiley Online Library
Varicocele is one of the most common causes of low semen quality, which is reflected in
high percentages of sperm cells with fragmented DNA. While varicocelectomy is usually …

[HTML][HTML] Magnetic-activated cell sorting (MACS): a useful sperm-selection technique in cases of high levels of sperm DNA fragmentation

A Pacheco, A Blanco, F Bronet, M Cruz… - Journal of Clinical …, 2020 - mdpi.com
Magnetic-activated cell sorting (MACS) can be used to separate apoptotic sperm with high
proportions of fragmented DNA from the rest, thus improving the overall quality of the …

[PDF][PDF] Male factor infertility outcomes using magnetic activated cell sorting in intra citoplasmatic sperm injection cycles

FE Horta, J Crosby, A Mackenna… - Andrology-Open …, 2016 - research.monash.edu
Sperm DNA fragmentation can have negative consequences in clinical outcomes of couples
undergoing Assisted Reproductive Technologies (ART). Sperm separation techniques are …