Interleukin 17A participates in renal inflammation associated to experimental and human hypertension
M Orejudo, RR Rodrigues-Diez… - Frontiers in …, 2019 - frontiersin.org
Hypertension is now considered as an inflammatory disease, and the kidney is a key end-
organ target. Experimental and clinical studies suggest that interleukin 17A (IL-17A) is a …
organ target. Experimental and clinical studies suggest that interleukin 17A (IL-17A) is a …
Interleukin 17A: key player in the pathogenesis of hypertension and a potential therapeutic target
GK Davis, DJ Fehrenbach, MS Madhur - Current hypertension reports, 2021 - Springer
Abstract Purpose of Review To summarize key advances in our understanding of the role of
interleukin 17A (IL-17A) in the pathogenesis of hypertension and highlight important areas …
interleukin 17A (IL-17A) in the pathogenesis of hypertension and highlight important areas …
[HTML][HTML] IL-17C has a pathogenic role in kidney ischemia/reperfusion injury
Cytokines are necessary to trigger the inflammatory response in kidney
ischemia/reperfusion injury. Interleukin-17C (IL-17C), a unique member of the IL-17 family …
ischemia/reperfusion injury. Interleukin-17C (IL-17C), a unique member of the IL-17 family …
Interleukin-17A regulates renal sodium transporters and renal injury in angiotensin II–induced hypertension
Angiotensin II–induced hypertension is associated with an increase in T-cell production of
interleukin-17A (IL-17A). Recently, we reported that IL-17A−/− mice exhibit blunted …
interleukin-17A (IL-17A). Recently, we reported that IL-17A−/− mice exhibit blunted …
The role of interleukin-17A in the pathogenesis of kidney diseases
C Cortvrindt, R Speeckaert, A Moerman, JR Delanghe… - Pathology, 2017 - Elsevier
Being a member of the IL-17 family, comprising six structurally related ligands, IL-17A is a
cytokine, produced by multiple cell types, such as CD4+ αβ T cells, γδ T cells, natural killer …
cytokine, produced by multiple cell types, such as CD4+ αβ T cells, γδ T cells, natural killer …
Interleukin 17A promotes diabetic kidney injury
J Ma, YJ Li, X Chen, T Kwan, SJ Chadban, H Wu - Scientific reports, 2019 - nature.com
The role of the pro-inflammatory cytokine IL-17 in the pathogenesis of numerous
inflammatory disorders is well-documented, but conflicting results are reported for its role in …
inflammatory disorders is well-documented, but conflicting results are reported for its role in …
IL-17F promotes tissue injury in autoimmune kidney diseases
JH Riedel, HJ Paust, S Krohn, JE Turner… - Journal of the …, 2016 - journals.lww.com
The TH 17 immune response has a central role in the pathogenesis of autoimmune
diseases, implicating the TH 17 master cytokine, IL-17A, as the critical mediator of diseases …
diseases, implicating the TH 17 master cytokine, IL-17A, as the critical mediator of diseases …
IL-17 in renal immunity and autoimmunity
PS Biswas - The Journal of Immunology, 2018 - journals.aai.org
The kidney is an organ particularly susceptible to damage caused by infections and
autoimmune conditions. Renal inflammation confers protection against microbial infections …
autoimmune conditions. Renal inflammation confers protection against microbial infections …
Interleukin-17A induces vascular remodeling of small arteries and blood pressure elevation
M Orejudo, AB García-Redondo… - Clinical …, 2020 - portlandpress.com
An important link exists between hypertension and inflammation. Hypertensive patients
present elevated circulating levels of proinflammatory cytokines, including interleukin-17A …
present elevated circulating levels of proinflammatory cytokines, including interleukin-17A …
Role of interleukin-23/interleukin-17 axis in T-cell-mediated actions in hypertension
Current knowledge suggests that hypertension is in part mediated by immune mechanisms.
Both interleukin (IL)-23 and IL-17 are up-regulated in several experimental hypertensive …
Both interleukin (IL)-23 and IL-17 are up-regulated in several experimental hypertensive …
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