Vaccination with the polymorphic membrane protein A reduces Chlamydia muridarum induced genital tract pathology
T Müller, E Becker, S Stallmann, A Waldhuber… - Vaccine, 2017 - Elsevier
Chlamydia trachomatis serovars DK are one of the most frequent causes of sexually
transmitted infections of the female genital tract, with possible complications such as …
transmitted infections of the female genital tract, with possible complications such as …
Chlamydia muridarum Major Outer Membrane Protein‐Specific Antibodies Inhibit In Vitro Infection but Enhance Pathology In Vivo
KA Cunningham, AJ Carey, L Hafner… - American Journal of …, 2011 - Wiley Online Library
Citation Cunningham KA, Carey AJ, Hafner L, Timms P, Beagley KW. Chlamydia muridarum
major outer membrane protein‐specific antibodies inhibit in vitro infection but enhance …
major outer membrane protein‐specific antibodies inhibit in vitro infection but enhance …
Immunization with an acellular vaccine consisting of the outer membrane complex of Chlamydia trachomatis induces protection against a genital challenge
S Pal, I Theodor, EM Peterson… - Infection and …, 1997 - Am Soc Microbiol
The ability to induce protection against a genital challenge was studied in BALB/c female
mice with three Chlamydia trachomatis mouse pneumonitis (MoPn) major outer membrane …
mice with three Chlamydia trachomatis mouse pneumonitis (MoPn) major outer membrane …
Heterotypic protection of mice against chlamydial salpingitis and colonization of the lower genital tract with a human serovar F isolate of Chlamydia trachomatis by …
M Tuffrey, F Alexander, W Conlan, C Woods… - …, 1992 - microbiologyresearch.org
Intrauterine infection of mice with a human genital tract isolate of Chlamydia trachomatis
(serovar F) resulted in salpingitis. In some cases, oviduct damage was sufficient to cause …
(serovar F) resulted in salpingitis. In some cases, oviduct damage was sufficient to cause …
Vaccination with MIP or Pgp3 induces cross-serovar protection against chlamydial genital tract infection in mice
X Luan, B Peng, Z Li, L Tang, C Chen, L Chen, H Wu… - Immunobiology, 2019 - Elsevier
Previously we reported that recombinant Chlamydia muridarum macrophage infectivity
potentiator (MIP) provided partial protection against C. muridarum genital tract infection in …
potentiator (MIP) provided partial protection against C. muridarum genital tract infection in …
Immunity to murine chlamydial genital infection
RP Morrison, HD Caldwell - Infection and immunity, 2002 - Am Soc Microbiol
Chlamydia trachomatis sexually transmitted infections cause considerable morbidity and
socioeconomic burden worldwide, despite significant advances in our understanding of the …
socioeconomic burden worldwide, despite significant advances in our understanding of the …
Immunization with chlamydial type III secretion antigens reduces vaginal shedding and prevents fallopian tube pathology following live C. muridarum challenge
DC Bulir, S Liang, A Lee, S Chong, E Simms, C Stone… - Vaccine, 2016 - Elsevier
Chlamydia trachomatis infections in women are often asymptomatic and if left untreated can
lead to significant late sequelae including pelvic inflammatory disease and tubal factor …
lead to significant late sequelae including pelvic inflammatory disease and tubal factor …
Subclinical chlamydial infection of the female mouse genital tract generates a potent protective immune response: implications for development of live attenuated …
H Su, R Messer, W Whitmire, S Hughes… - Infection and …, 2000 - Am Soc Microbiol
Chlamydia trachomatis is a major cause of sexually transmitted disease (STD) for which a
vaccine is needed. CD4+ T-helper type 1 (Th1) cell-mediated immunity is an important …
vaccine is needed. CD4+ T-helper type 1 (Th1) cell-mediated immunity is an important …
CD4+ T Cells and Antibody Are Required for Optimal Major Outer Membrane Protein Vaccine-Induced Immunity to Chlamydia muridarum Genital Infection
CM Farris, SG Morrison, RP Morrison - Infection and immunity, 2010 - Am Soc Microbiol
Despite effective antimicrobial chemotherapy, control of Chlamydia trachomatis urogenital
infection will likely require a vaccine. We have assessed the protective effect of an outer …
infection will likely require a vaccine. We have assessed the protective effect of an outer …
Induction of protection against vaginal shedding and infertility by a recombinant Chlamydia vaccine
A vaccine formulated with the Chlamydia muridarum recombinant major outer membrane
protein, plus the adjuvants CpG and Montanide, was tested for its ability to protect BALB/c …
protein, plus the adjuvants CpG and Montanide, was tested for its ability to protect BALB/c …