The penetration of biological membranes is a prime obstacle for the delivery of
pharmaceutical drugs. Cell-penetrating peptide (CPP) is an efficient vehicle that can deliver …

Biological cell membranes are a natural barrier for living cells. In the last few decades, the
cell membrane has been the main hurdle in the efficient delivery of bioactive and therapeutic …

An important hurdle for the intracellular delivery of large cargo is the cellular membrane,
which protects the cell from exogenous substances. Cell-penetrating peptides (CPPs) can …

Cell-penetrating peptides (CPPs) are small molecules of major interest due to their ability to
efficiently transport cargos across cell membranes in a receptor-and energy-independent …

Cell‐penetrating peptides (CPPs) can transport various cargoes through membranes of live
cells. Since the first generations of CPPs suffered from insufficient cell and tissue selectivity …

The permeability barrier imposed by cellular membranes limits the access of exogenous
compounds to the interior of cells. Researchers and patients alike would benefit from …

The hydrophilic nature of peptides and proteins renders them impermeable to cell
membranes. Thus, in order to successfully deliver peptide and protein-based therapeutics …

The recent discovery of new potent therapeutic molecules that do not reach the clinic due to
poor delivery and low bioavailability have made of delivery a key stone in therapeutic …

The selective infiltration of cell membranes and tissue barriers often blocks the entry of most
active molecules. This natural defense mechanism prevents the invasion of exogenous …

The selective permeability of the plasma membrane prohibits most exogenous agents from
gaining cellular access. Since many therapeutics and reporter molecules must be …