Mechanism and regulation of co-transcriptional mRNP assembly and nuclear mRNA export
W Wende, P Friedhoff, K Sträßer - The biology of mRNA: structure and …, 2019 - Springer
Abstract mRNA is the “hermes” of gene expression as it carries the information of a protein-
coding gene to the ribosome. Already during its synthesis, the mRNA is bound by mRNA …
coding gene to the ribosome. Already during its synthesis, the mRNA is bound by mRNA …
Cotranscriptional mRNP assembly: from the DNA to the nuclear pore
A Aguilera - Current opinion in cell biology, 2005 - Elsevier
Transcription is coupled with the concomitant assembly of RNA-binding proteins to the
nascent mRNA to generate a stable and export-competent mRNP particle. RNA-binding …
nascent mRNA to generate a stable and export-competent mRNP particle. RNA-binding …
Biogenesis of mRNPs: integrating different processes in the eukaryotic nucleus
Transcription is a central function occurring in the nucleus of eukaryotic cells in coordination
with other nuclear processes. During transcription, the nascent pre-mRNA associates with …
with other nuclear processes. During transcription, the nascent pre-mRNA associates with …
Co‐transcriptional mRNP formation is coordinated within a molecular mRNP packaging station in S. cerevisiae
DM Meinel, K Sträßer - Bioessays, 2015 - Wiley Online Library
In eukaryotes, the messenger RNA (mRNA), the blueprint of a protein‐coding gene, is
processed and packaged into a messenger ribonucleoprotein particle (mRNP) by mRNA …
processed and packaged into a messenger ribonucleoprotein particle (mRNP) by mRNA …
Keeping mRNPs in check during assembly and nuclear export
The cell nucleus is an intricate organelle that coordinates multiple activities that are
associated with DNA replication and gene expression. In all eukaryotes, it stores the genetic …
associated with DNA replication and gene expression. In all eukaryotes, it stores the genetic …
How cells get the message: dynamic assembly and function of mRNA–protein complexes
M Müller-McNicoll, KM Neugebauer - Nature Reviews Genetics, 2013 - nature.com
Abstract mRNA is packaged into ribonucleoprotein particles called mRNPs. A multitude of
RNA-binding proteins as well as a host of associated proteins participate in the fate of …
RNA-binding proteins as well as a host of associated proteins participate in the fate of …
[HTML][HTML] Early formation of mRNP: license for export or quality control?
TH Jensen, K Dower, D Libri, M Rosbash - Molecular cell, 2003 - cell.com
Eukaryotic mRNA is processed by enzymes and packaged with proteins within nuclei to
generate functional messenger ribonucleoprotein (mRNP) particles. Processing and …
generate functional messenger ribonucleoprotein (mRNP) particles. Processing and …
[HTML][HTML] Regulation of mRNA trafficking by nuclear pore complexes
A Bonnet, B Palancade - Genes, 2014 - mdpi.com
Over the last two decades, multiple studies have explored the mechanisms governing
mRNA export out of the nucleus, a crucial step in eukaryotic gene expression. During …
mRNA export out of the nucleus, a crucial step in eukaryotic gene expression. During …
[HTML][HTML] Spatial organization of single mRNPs at different stages of the gene expression pathway
Summary mRNAs form ribonucleoprotein complexes (mRNPs) by association with proteins
that are crucial for mRNA metabolism. While the mRNP proteome has been well …
that are crucial for mRNA metabolism. While the mRNP proteome has been well …