[HTML][HTML] Current knowledge and novel frontiers in lower urinary tract dysfunction after spinal cord injury: Basic research perspectives

N Wada, S Karnup, K Kadekawa, N Shimizu… - Urological …, 2022 - journals.lww.com
This review article aims to summarize the recent advancement in basic research on lower
urinary tract dysfunction (LUTD) following spinal cord injury (SCI) above the sacral level. We …

Molecular mechanisms of neurogenic lower urinary tract dysfunction after spinal cord injury

N Shimizu, T Saito, N Wada, M Hashimoto… - International Journal of …, 2023 - mdpi.com
This article provides a synopsis of current progress made in fundamental studies of lower
urinary tract dysfunction (LUTD) after spinal cord injury (SCI) above the sacral level. Animal …

Assessing Neurogenic Lower Urinary Tract Dysfunction after Spinal Cord Injury: Animal Models in Preclinical Neuro-Urology Research

AW Doelman, F Streijger, SJA Majerus, MS Damaser… - Biomedicines, 2023 - mdpi.com
Neurogenic bladder dysfunction is a condition that affects both bladder storage and voiding
function and remains one of the leading causes of morbidity after spinal cord injury (SCI) …

Time-dependent progression of neurogenic lower urinary tract dysfunction after spinal cord injury in the mouse model

T Saito, D Gotoh, N Wada, P Tyagi… - American Journal …, 2021 - journals.physiology.org
This study evaluated the time-course changes in bladder and external urinary sphincter
(EUS) activity and the expression of mechanosensitive channels in lumbosacral dorsal root …

Bladder afferent pathway and spinal cord injury: possible mechanisms inducing hyperreflexia of the urinary bladder

N Yoshimura - Progress in neurobiology, 1999 - Elsevier
Lower urinary tract dysfunction is a common problem in patients with spinal cord injury (SCI).
Since the coordination of the urinary bladder and urethra is controlled by the complex …

Spinal reflex control of micturition after spinal cord injury

C Tai, JR Roppolo, WC de Groat - Restorative neurology and …, 2006 - content.iospress.com
Purpose: This review summarizes possible spinal reflexes involved in micturition control as
well as current treatments for lower urinary tract dysfunction after spinal cord injury (SCI) in …

[HTML][HTML] Non-invasive neuromodulation of spinal cord restores lower urinary tract function after paralysis

PN Gad, E Kreydin, H Zhong, K Latack… - Frontiers in …, 2018 - frontiersin.org
It is commonly assumed that restoration of locomotion is the ultimate goal after spinal cord
injury (SCI). However, lower urinary tract (LUT) dysfunction is universal among SCI patients …

Pharmacologic and potential biologic interventions to restore bladder function after spinal cord injury

N Yoshimura, CP Smith, MB Chancellor… - Current opinion in …, 2000 - journals.lww.com
Spinal cord injury disrupts voluntary control of voiding and the normal reflex pathways that
coordinate bladder and urethral sphincter function. The present review addresses studies in …

Spinal cord injury and bladder dysfunction: new ideas about an old problem

CD Cruz, F Cruz - The scientific world journal, 2011 - Wiley Online Library
Control of the lower urinary tract (LUT) requires complex neuronal circuits that involve
elements located at the peripheral nervous system and at different levels of the central …

Changes in bladder and external urethral sphincter function after spinal cord injury in the rat

MN Kruse, AL Belton… - American Journal of …, 1993 - journals.physiology.org
Spinal cord injury (SCI) in humans results in inappropriate contractions of the external
urethral sphincter muscle (EUS) during micturition (bladder-sphincter dyssynergia), leading …