Exercise performance is determined by oxygen supply to working muscles and vital organs.
In healthy individuals, exercise performance is limited in the hypoxic environment at altitude …

Background Many patients with pulmonary arterial or chronic thromboembolic pulmonary
hypertension (PH) wish to travel to altitude or by airplane, but their risk of hypoxia-related …

Hypoxic pulmonary vasoconstriction may limit aerobic exercise capacity at high altitude by
two different mechanisms, which both affect the convectional transport of oxygen to the …

It is well-established that different altitude training modalities can improve convective oxygen
(O2) transport capacity and physical fitness of athletes (Millet et al., 2010). Exercising in …

The objective of these experiments was to determine whether living and training in moderate
hypoxia (MHx) confers an advantage on maximal normoxic exercise capacity compared with …

Ascent to altitude uniformly reduces exercise capacity. Even following acclimatization,
maximal oxygen consumption (VO2max) remains well below sea level values (Calbet et al …

The literature suggests that acute hypobaric (HH) and normobaric (NH) hypoxia exposure
elicits different physiological responses. Only limited information is available on whether …

To test the hypothesis that maximal exercise pulmonary ventilation (̇ VE _\max) is a limiting
factor affecting maximal oxygen uptake (̇ VO _ 2 max) in moderate hypobaric hypoxia (H) …

Our laboratory has previously shown an attenuation of hypoxic pulmonary hypertension by
exercise training (ET)(Henderson KK, Clancy RL, and Gonzalez NC. J Appl Physiol 90: 2057 …

To determine the interactions between endurance training and hypoxia on maximal exercise
performance, we performed a study on sedentary high-altitude natives who were trained in …