[HTML][HTML] Superantigens, a paradox of the immune response

S Noli Truant, DM Redolfi, MB Sarratea, EL Malchiodi… - Toxins, 2022 - mdpi.com
Staphylococcal enterotoxins are a wide family of bacterial exotoxins with the capacity to
activate as much as 20% of the host T cells, which is why they were called superantigens …

Diversity in Staphylococcus aureus enterotoxins

D Thomas, S Chou, O Dauwalder, G Lina - Superantigens and …, 2007 - karger.com
The molecular mechanism of Staphylococcus aureus phathogenicity is complex and
involves several toxins, including the famous staphylococcal enterotoxin (SE) and toxic …

Staphylococcal Enterotoxins A, D, and E: Structure and Function, Including Mechanism of T-Cell Superantigenicity

LA Svensson, EM Schad, M Sundström… - Preparative …, 1997 - Taylor & Francis
Staphylococcal enterotoxins (SEs) are a family of structurally related exotoxin molecules
produced by certain Gram-positive Staphylococcus aureus bacterial strains. SEs are a major …

[HTML][HTML] Update on molecular diversity and multipathogenicity of staphylococcal superantigen toxins

DL Hu, S Li, R Fang, HK Ono - Animal Diseases, 2021 - Springer
Staphylococcal superantigen (SAg) toxins are the most notable virulence factors associated
with Staphylococcus aureus, which is a pathogen associated with serious community and …

[HTML][HTML] Superantigens of a superbug: Major culprits of Staphylococcus aureus disease?

MJ Aman - Virulence, 2017 - Taylor & Francis
Infections with multidrug resistant (MDR) bacteria represent a major challenge for public
health. Methicillin resistant S. aureus (MRSA) is one of the leading causes of hospital and …

[HTML][HTML] Allergy—A New Role for T Cell Superantigens of Staphylococcus aureus?

G Abdurrahman, F Schmiedeke, C Bachert, BM Bröker… - Toxins, 2020 - mdpi.com
Staphylococcus aureus superantigens (SAgs) are among the most potent T cell mitogens
known. They stimulate large fractions of T cells by cross-linking their T cell receptor with …

[HTML][HTML] Staphylococcal superantigens in colonization and disease

SX Xu, JK McCormick - Frontiers in cellular and infection microbiology, 2012 - frontiersin.org
Superantigens (SAgs) are a family of potent immunostimulatory exotoxins known to be
produced by only a few bacterial pathogens, including Staphylococcus aureus. More than …

Superantigens: just like peptides only different

T Proft, J Fraser - The Journal of experimental medicine, 1998 - rupress.org
The exotoxins produced by Staphylococcus aureus and Streptococcus pyogenes are
prototype molecules for the larger family of superantigens (SAGs). This family now includes …

[PDF][PDF] Bacterial superantigens and superantigen-like toxins

RJ Langley, JD Fraser, T Proft - The Comprehensive Sourcebook …, 2015 - researchgate.net
The term superantigen (SAg) was coined in 1989 in the research group of Philippa Marrack
and John Kappler and describes a group of proteins with extremely high potency to …

[HTML][HTML] Staphylococcal superantigens spark host-mediated danger signals

T Krakauer, K Pradhan, BG Stiles - Frontiers in immunology, 2016 - frontiersin.org
Staphylococcal enterotoxin B (SEB) of Staphylococcus aureus, and related superantigenic
toxins produced by myriad microbes, are potent stimulators of the immune system causing a …