Botulinum toxin in the management of children with cerebral palsy

I Multani, J Manji, T Hastings-Ison, A Khot, K Graham - Pediatric Drugs, 2019 - Springer
During the past 25 years, botulinum toxin type A (BoNT-A) has become the most widely used
medical intervention in children with cerebral palsy. In this review we consider the gaps in …

Long‐term effects of botulinum toxin A in children with cerebral palsy

K Tedroff, F Granath, H Forssberg… - … Medicine & Child …, 2009 - Wiley Online Library
The long‐term effects of botulinum toxin A (BoNT‐A) treatment in children with cerebral
palsy (CP) are still elusive. We studied a prospective clinical cohort of 94 children with …

Best clinical practice in botulinum toxin treatment for children with cerebral palsy

W Strobl, T Theologis, R Brunner, S Kocer… - Toxins, 2015 - mdpi.com
Botulinum toxin A (BoNT-A) is considered a safe and effective therapy for children with
cerebral palsy (CP), especially in the hands of experienced injectors and for the majority of …

The use of botulinum toxin A in children with cerebral palsy, with a focus on the lower limb

G Molenaers, A Van Campenhout… - Journal of children's …, 2010 - journals.sagepub.com
Purpose The purpose of this review is to clarify the role of botulinum toxin serotype A (BTX-
A) in the treatment of children with cerebral palsy (CP), with a special focus on the lower …

Botulinum toxin assessment, intervention and after‐care for lower limb spasticity in children with cerebral palsy: international consensus statement

SC Love, I Novak, M Kentish… - European journal of …, 2010 - Wiley Online Library
Botulinum neurotoxin type‐A (BoNT‐A) has been used in association with other
interventions in the management of spasticity in children with cerebral palsy (CP) for almost …

Functional outcomes of intramuscular botulinum toxin type A in the upper limbs of children with cerebral palsy: a phase II trial

MA Wallen, SJ O'Flaherty, MCA Waugh - Archives of physical medicine and …, 2004 - Elsevier
Wallen MA, O'Flaherty SJ, Waugh M-CA. Functional outcomes of intramuscular botulinum
toxin type A in the upper limbs of children with cerebral palsy: a phase II trial. Arch Phys Med …

Double-blind comparison study of two doses of botulinum toxin A injected into calf muscles in children with hemiplegic cerebral palsy

F Polak, R Morton, C Ward, WA Wallace… - … medicine and child …, 2002 - cambridge.org
Despite several trials showing reductions in tone and improvements in gait, the relation
between botulinum toxin A (BTX-A) dose and response has rarely been investigated. A …

Botulinum toxin treatment of children with cerebral palsy—a short review of different injection techniques

AS Schroeder, S Berweck, SH Lee, F Heinen - Neurotoxicity research, 2006 - Springer
The intramuscular application of botulinum toxin type A (BoNT/A) has emerged to be an
established treatment option to reduce muscular hyperactivity due to spasticity in children …

Botulinum toxin A in management of cerebral palsy

R Calderon-Gonzalez, R Calderon-Sepulveda… - Pediatric Neurology, 1994 - Elsevier
The efficacy of local injection of botulinum toxin A in selected skeletal muscles to relieve
muscle hypertonia and muscle contracture, and increase range of motion in children with …

Randomised double blind placebo controlled trial of the effect of botulinum toxin on walking in cerebral palsy

T Ubhi, BB Bhakta, HL Ives, V Allgar… - Archives of disease in …, 2000 - adc.bmj.com
BACKGROUND Cerebral palsy is the commonest cause of severe physical disability in
childhood. For many years treatment has centred on the use of physiotherapy and orthotics …