The efficacy of atorvastatin has been compared with lovastatin, pravastatin and simvastatin
in three large multicenter trials. Atorvastatin at its starting dose of 10 mg/day provided …

Objective: At higher doses, simvastatin has been shown to produce significantly greater
increases in high-density lipoprotein (HDL) cholesterol and apolipoprotein (apo) AI than …

We directly compared the safety and efficacy of atorvastatin and simvastatin in
hypercholesterolemic patients. This 1-year, randomized, double-blind study was performed …

Background: A close relationship exists between high levels of total cholesterol
(TC)(particularly low-density lipoprotein cholesterol [LDL-C]) and low levels of high-density …

Background Previous trials have demonstrated that lowering low-density lipoprotein (LDL)
cholesterol levels below currently recommended levels is beneficial in patients with acute …

This 6-week Prospective, Randomized, Open-label Blinded End point (PROBE) study
conducted at 12 sites in the United States compared the efficacy and safety of atorvastatin …

Objective: This multicenter, open-label, randomized, parallel-arm study was undertaken to
compare the efficacy and safety of atorvastatin 10, 20, and 40 mg/d with usual care in high …

Extensive data are available on the safety of atorvastatin from randomised clinical trials,
postmarketing analyses and reports to regulatory agencies. Atorvastatin is generally well …

Placebo-controlled clinical trials have shown that atorvastatin is beneficial in patients with
myocardial ischemia, established coronary artery disease, hypertension and 3 other …

Background: Atorvastatin, a new enantiomerically pure synthetic statin, has shown a marked
low-density lipoprotein (LDL) cholesterol reduction at doses ranging from 10 to 80 mg/d …