A series of 72 acridine and azaacridinie derivatives have been tested as inhibitors of Ca2"-
and phospholipid-activated protein kinase C (PK (C), the catalytic subunit of cyclic AMP …

A series of nine tetrahydroacridine derivatives with iodobenzoic moiety were synthesized
and evaluated for their cytotoxic activity against cancer cell lines—A549 (human lung …

During the last 4 decades, intensive research has focussed on the effect of small organic
molecules with antitumour activity that are able to intercalate into DNA and inhibit …

Eleven novel acridone derivatives were synthesized and evaluated for their anticancer
activity against 60 human cancer cell lines. Five compounds 8b, 8d, 8g, 8h, and 8k …

Acridine compounds consist of a base structure similar to anthracene but with one of the
central carbon-hydrogen groups replaced by Nitrogen and are being widely researched as …

Targeting dihydrofolate reductase, here, we report the tumor growth inhibitory activity of
substituted acridones. The screening of the molecules over 60 cell line panel of human …

Several acridine derivatives have been screened for their therapeutic potential and some
are already established as antiprotozoan, antibacterial or anticancer agents. However …

Acridines have been studied for several decades because of their numerous biological
effects, especially anticancer activity. Recently, cytotoxicity of novel acridine derivatives, 3, 6 …

Lung cancer is still the leading cause of cancer-related death worldwide, indicating a
necessity to develop more effective therapy. Acridine derivatives are potential anticancer …

FR2926550B1 - Derives de tetrahydrocyclopentac!acridines inhibiteurs de kinases et leurs
applications biologiques - Google Patents FR2926550B1 - Derives de …