I5 Bioavailability and anti-diabetic action of naturally-occurring flavonoids and phenolic acids

G Williamson - Biochemical Pharmacology, 2017 - Elsevier
Flavonoids and phenolic acids (polyphenols) are naturally-occurring bioactive compounds
from plants, often found in high amounts in many foods and beverages. They are also …

The emerging role of polyphenols in the management of type 2 diabetes

Y Wang, H Alkhalidy, D Liu - Molecules, 2021 - mdpi.com
Type 2 diabetes (T2D) is a fast-increasing health problem globally, and it results from insulin
resistance and pancreatic β-cell dysfunction. The gastrointestinal (GI) tract is recognized as …

Antioxidant, anti-inflammatory, and metabolic properties of tocopherols and tocotrienols: clinical implications for vitamin E supplementation in diabetic kidney disease

A Di Vincenzo, C Tana, H El Hadi, C Pagano… - International Journal of …, 2019 - mdpi.com
Diabetes mellitus is a metabolic disorder characterized by the development of vascular
complications associated with high morbidity and mortality and the consequent relevant …

Natural phyto-bioactive compounds for the treatment of type 2 diabetes: inflammation as a target

S Gothai, P Ganesan, SY Park, S Fakurazi, DK Choi… - Nutrients, 2016 - mdpi.com
Diabetes is a metabolic, endocrine disorder which is characterized by hyperglycemia and
glucose intolerance due to insulin resistance. Extensive research has confirmed that …

Natural polyphenols as anti-oxidant, anti-inflammatory and anti-angiogenic agents in the metabolic syndrome

R Negrão, A Faria - Oxidative stress, inflammation and angiogenesis in …, 2009 - Springer
The world is increasingly threatened by chronic diseases, related to lifestyle, stress, lack of
physical exercise and excessive intake of high caloric diets. Almost all chronic diseases …

Recent insights into the nutritional antioxidant therapy in prevention and treatment of diabetic vascular complications: a comprehensive review

NM Beeraka, IK Tomilova, GA Batrak… - Current Medicinal …, 2022 - ingentaconnect.com
Diabetes mellitus (DM) and DM-induced vascular complications are significant global
healthcare problems, causing a decrease in patient quality of life. The main reason for the …

Combined effect of interventions with pure or enriched mixtures of (poly) phenols and anti-diabetic medication in type 2 diabetes management: a meta-analysis of …

AF Raimundo, F Félix, R Andrade… - European journal of …, 2020 - Springer
Purpose (Poly) phenols have been reported to confer protective effects against type 2
diabetes but the precise association remains elusive. This meta-analysis aimed to assess …

Potential role of polyphenols in the prevention of cardiovascular diseases: molecular bases

JG Gormaz, N Valls, C Sotomayor… - Current medicinal …, 2016 - ingentaconnect.com
Cardiovascular diseases (CVD) are the leading cause of mortality worldwide. It is widely
accepted that oxidative stress plays a key role in their development and progression; hence …

Antioxidant for treatment of diabetic complications: A meta‐analysis and systematic review

O Zhong, J Hu, J Wang, Y Tan, L Hu… - Journal of Biochemical …, 2022 - Wiley Online Library
Antioxidants may provide a complementary treatment for patients with chronic diseases.
Nevertheless, studies that have measured the effects of antioxidant on diabetes …

Natural flavonoids as potential herbal medication for the treatment of diabetes mellitus and its complications

J Chen, S Mangelinckx, A Adams… - Natural product …, 2015 - journals.sagepub.com
Diabetes mellitus, together with its various complications, is becoming a serious threat to
human health. Natural products are secondary metabolites widely distributed in plants …