This narrative review aims to discuss the more relevant evidence on the role of linoleic acid
(LA), a n-6 essential fatty acid that constitutes the predominant proportion of dietary …

Cardiovascular disease (CVD) is the leading cause of death worldwide. Risk factors for
developing this disease include high serum concentrations of total cholesterol, triglycerides …

Epidemiologic studies have shown a beneficial association between polyunsaturated fatty
acid (PUFA), specifically linoleic acid (C18: 2, n-6), intake and cardiovascular disease …

The consumption of linoleic acid (LA, ω-6 18: 2), the most common ω-6 polyunsaturated fatty
acid (PUFA) in the Modern Western diet (MWD), has significantly increased over the last …

Over the course of the twentieth century, there was a 20-fold increase in consumption of
vegetable oils resulting both from their increased availability and from recommendations to …

It is now recognized that the amount and type of dietary fat consumed play an important role
in metabolic health. In humans, high intake of polyunsaturated fatty acids (PUFAs) has been …

Objective: To determine whether dietary supplementation with α linolenic acid (ALA) can
modify established and emerging cardiovascular risk markers. Design: Systematic review …

Linoleic acid (LA) and alpha linolenic acid (ALA) belong to the n− 6 (omega-6) and n− 3
(omega-3) series of polyunsaturated fatty acids (PUFA), respectively. They are defined …

Our understanding of the cardiovascular disease (CVD) benefits of α-linolenic acid (ALA, 18:
3n–3) has advanced markedly during the past decade. It is now evident that ALA benefits …

Background: Global dietary recommendations for and cardiovascular effects of linoleic acid,
the major dietary omega-6 fatty acid, and its major metabolite, arachidonic acid, remain …