[HTML][HTML] ω-6 polyunsaturated fatty acids and cardiometabolic health: current evidence, controversies, and research gaps

KC Maki, F Eren, ME Cassens, MR Dicklin… - Advances in …, 2018 - Elsevier
Abstract The 2015 Dietary Guidelines for Americans recommend limiting the intake of
saturated fatty acids (SFAs) to< 10% of energy/d and replacing dietary SFAs with …

Update on alpha-linolenic acid

AH Stark, MA Crawford, R Reifen - Nutrition reviews, 2008 - academic.oup.com
Consumption of omega 3 fatty acids is known to have health benefits. For many years, the
importance of the only member of the omega 3 family considered to be essential, alpha …

Dietary n-3 polyunsaturated fatty acids and amelioration of cardiovascular disease: possible mechanisms

JE Kinsella, B Lokesh, RA Stone - The American journal of clinical nutrition, 1990 - Elsevier
Consumption of n-3 polyunsaturated fatty acids (n-3 PUFAs) is associated with a reduced
incidence of coronary arterial diseases. Dietary n-3 PUFAs act via several mechanisms …

[HTML][HTML] Importance of dietary γ-linolenic acid in human health and nutrition

YY Fan, RS Chapkin - The Journal of nutrition, 1998 - Elsevier
Considerable debate remains regarding the distinct biological activities of individual
polyunsaturated fatty acids (PUFA). One of the most interesting yet controversial dietary …

Effects of dietary α-linolenic acid treatment and the efficiency of its conversion to eicosapentaenoic and docosahexaenoic acids in obesity and related diseases

M Takic, B Pokimica, G Petrovic-Oggiano, T Popovic - Molecules, 2022 - mdpi.com
The essential fatty acid alpha-linolenic acid (ALA) is present in high amounts in oils such as
flaxseed, soy, hemp, rapeseed, chia, and perilla, while stearidonic acid is abundant in …

The role of n− 6 and n− 3 polyunsaturated fatty acids in the manifestation of the metabolic syndrome in cardiovascular disease and non-alcoholic fatty liver disease

J Monteiro, M Leslie, MH Moghadasian, BM Arendt… - Food & function, 2014 - pubs.rsc.org
Cardiovascular disease (CVD) and non-alcoholic fatty liver disease (NAFLD) are
manifestations of the metabolic syndrome. CVD remains the number one cause of mortality …

Omega-3 fatty acids in cardiovascular disease–an uphill battle

C von Schacky - Prostaglandins, Leukotrienes and Essential Fatty Acids, 2015 - Elsevier
In cardiology, results of recent large intervention trials with eicosapentaenoic acid (EPA)
plus docosahexaenoic acid (DHA) supplements were neutral. In contrast, in epidemiologic …

Meta-analysis of the effects of n-3 polyunsaturated fatty acids on lipoproteins and other emerging lipid cardiovascular risk markers in patients with type 2 diabetes

J Hartweg, AJ Farmer, R Perera, RR Holman… - Diabetologia, 2007 - Springer
Aims/hypothesis To determine the effects of marine-derived n-3 polyunsaturated fatty acids
(PUFA) on established and emerging lipid and lipoprotein cardiovascular risk markers in …

The short overview on the relevance of fatty acids for human cardiovascular disorders

VS Shramko, YV Polonskaya, EV Kashtanova… - Biomolecules, 2020 - mdpi.com
This review presents existing evidence of the influence of saturated and unsaturated fatty
acids on cardiovascular diseases (CVD). Data are discussed regarding the roles of the most …

[HTML][HTML] Importance of maintaining a low omega–6/omega–3 ratio for reducing inflammation

JJ DiNicolantonio, JH O'Keefe - Open heart, 2018 - openheart.bmj.com
The consumption of seed oils high in the omega-6 polyunsaturated fat (PUFA) linoleic acid
(LA) contributes to low-grade inflammation, oxidative stress, endothelial dysfunction and …