Vitamin D plays a primary role in regulation of bone metabolism and calcium homeostasis.
Interestingly, emerging evidence suggests protective effects of vitamin D against liver …

Background Liver fibrosis may progress toward cirrhosis and cancer without effective
therapy. Here, we investigated the underlying mechanism of Vitamin D as a therapeutic …

Vitamin D was found to be involved in liver fibrosis modulation through binding to its
receptor (VDR) halting many fibrotic pathways. Targeting vitamin D-VDR axis using vitamin …

1, 25 (OH) 2D3, the active form of vitamin D, has an antiproliferative and antifibrotic effect on
hepatic stellate cells. Our aim was to investigate the potential of 1, 25 (OH) 2D3 to inhibit the …

Hepatic fibrosis is the net accumulation of matrix tissue components which controlled by pro-
fibrolytic enzymes, matrix metalloproteinases (MMPs), and pro-fibrotic cytokine, TGF-β1, and …

Background and aim Hepatic stellate cells (HSCs) are key participants in liver fibrosis
development. 1, 25 (OH) 2D3, the active form of vitamin D, has antiproliferative properties …

Objective Non-alcoholic fatty liver disease (NAFLD) is closely linked to obesity and
constitutes part of the metabolic syndrome, which have been associated with low serum …

There is ongoing evidence that vitamin D is related to the pathophysiology of cirrhosis.
Although the incidence of vitamin D deficiency in chronic liver diseases and cirrhosis is …

In animal models and human cross-sectional studies, vitamin D deficiency has been
associated with liver disease progression. Vitamin D supplementation has been suggested …

Vitamin D is becoming increasingly accepted as an important physiological regulator
outside of its classical role in skeletal homeostasis. A growing body of evidence connects …