Recent advances on CD4+ T cells in atherosclerosis and its implications for therapy

C Grönberg, J Nilsson, M Wigren - European Journal of Pharmacology, 2017 - Elsevier
Atherosclerosis is an arterial inflammatory disease and the primary cause of cardiovascular
disease. T helper (Th) cells are an important part in atherosclerotic plaque as they can be …

T cell subsets and functions in atherosclerosis

R Saigusa, H Winkels, K Ley - Nature Reviews Cardiology, 2020 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall and the primary
underlying cause of cardiovascular disease. Data from in vivo imaging, cell-lineage tracing …

Targeting T cells to treat atherosclerosis: odyssey from bench to bedside

J Bullenkamp, S Dinkla, JC Kaski… - European Heart …, 2016 - academic.oup.com
More than 150 years from the initial description of inflammation in atherosclerotic plaques,
randomized clinical trials to test anti-inflammatory therapies in atherosclerosis have recently …

The emerging role of Th1 cells in atherosclerosis and its implications for therapy

J Chen, X Xiang, L Nie, X Guo, F Zhang… - Frontiers in …, 2023 - frontiersin.org
Atherosclerosis is a chronic progressive inflammatory disease of the large and medium-
sized artery walls. The molecular mechanisms regulating the onset and progression of …

The many faces of CD8+ T cells in atherosclerosis

J van Duijn, J Kuiper, B Slütter - Current opinion in lipidology, 2018 - journals.lww.com
The many faces of CD8+ T cells in atherosclerosis : Current Opinion in Lipidology The many
faces of CD8+ T cells in atherosclerosis : Current Opinion in Lipidology Log in or Register …

T Cells in Atherosclerosis: Key Players in the Pathogenesis of Vascular Disease

H Hinkley, DA Counts, E VonCanon, M Lacy - Cells, 2023 - mdpi.com
Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of lipid-
rich plaques within arterial walls. T cells play a pivotal role in the pathogenesis of …

Regulatory T cells in atherosclerosis: is adoptive cell therapy possible?

AV Churov, YS Chegodaev, VA Khotina, VP Ofitserov… - Life, 2023 - mdpi.com
Simple Summary Atherosclerosis is a vascular disease with an asymptomatic debut and
development over decades. The mechanisms of progression of atherosclerosis are not …

T cell-based therapies for atherosclerosis

D FJ Ketelhuth, A Gistera… - Current …, 2013 - ingentaconnect.com
Cardiovascular diseases (CVDs), largely due to atherosclerosis, are the major causes of
death in today's world. Atherosclerosis is a chronic inflammatory condition initiated by …

Mechanisms of disease: the evolving role of regulatory T cells in atherosclerosis

J George - Nature Clinical Practice Cardiovascular Medicine, 2008 - nature.com
Atherosclerosis and related complications still represent the major cause of morbidity and
mortality in the western world. The mechanisms that govern the progression and …

Protective and pathogenic roles of CD8+ T cells in atherosclerosis

C Cochain, A Zernecke - Basic research in cardiology, 2016 - Springer
Although infiltration of CD8+ T cells in human atherosclerotic lesions has been described 30
years ago, the role of these cells in lesion development has long remained enigmatic. While …