Statins significantly reduce cardiovascular-related morbidity and mortality in patients with
and without coronary artery disease. The potential of this drug class has yet to be fully …

There is interindividual variation in lipid-lowering response to statins. The objective of this
study was to investigate whether common variation in genes involved in lipid and statin …

Substantial data from cell culture and animal studies evidence the preventive effect of
statins, cholesterol lowering-drugs, in regulation of cancer cell proliferation and metastasis …

ContextPolymorphisms in genes involved in cholesterol synthesis, absorption, and transport
may affect statin efficacy. ObjectiveTo evaluate systematically whether genetic variation …

Statins inhibit the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase,
which is required for cholesterol biosynthesis, and are beneficial in the primary and …

Pharmacogenomics of statin therapy: any new insights in effi... : Current Opinion in
Lipidology Pharmacogenomics of statin therapy: any new insights in efficacy or safety …

Statins are a class of oral drugs that are widely used for treatment of hypercholesterolemia.
Recent clinical data suggest that chronic use of these drugs increases the frequency of new …

Coronary artery disease (CAD) and its complications are the major causes of death in the
world. Although statins have been used to lower lipid levels in CAD patients, this goal can …

Statins are commonly used for reducing cardiovascular disease risk but therapeutic benefit
and reductions in levels of low-density lipoprotein cholesterol (LDL-C) vary among …

Statins have been reported to lower the risk of developing Alzheimer's disease; however, the
mechanism of this potentially important neuroprotective action is not understood. Lowering …